ImageDoubler: image-based doublet identification in single-cell sequencing

ImageDoubler: image-based doublet identification in single-cell sequencing

Abstract Single-cell sequencing provides detailed insights into individual cell behaviors within complex systems based on the assumption that each cell is uniquely isolated. However, doublets—where two or more cells are sequenced together—disrupt this assumption and can lead to potential data misint...

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Bibliographic Details
Main Authors: Kaiwen Deng, Xinya Xu, Manqi Zhou, Hongyang Li, Evan T. Keller, Gregory Shelley, Annie Lu, Lana Garmire, Yuanfang Guan
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55434-0
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