Cardiac Resynchronisation with Conduction System Pacing

To date, biventricular pacing (BiVP) has been the standard pacing modality for cardiac resynchronisation therapy. However, it is non-physiological, with the activation spreading between the left ventricular epicardium and right ventricular endocardium. Up to one-third of patients with heart failure...

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Main Authors: Fatima M Ezzeddine, Isaac G Leon, Yong-Mei Cha
Format: Article
Language:English
Published: Radcliffe Medical Media 2023-08-01
Series:Arrhythmia & Electrophysiology Review
Online Access:https://www.aerjournal.com/articleindex/aer.2023.03
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author Fatima M Ezzeddine
Isaac G Leon
Yong-Mei Cha
author_facet Fatima M Ezzeddine
Isaac G Leon
Yong-Mei Cha
author_sort Fatima M Ezzeddine
collection DOAJ
description To date, biventricular pacing (BiVP) has been the standard pacing modality for cardiac resynchronisation therapy. However, it is non-physiological, with the activation spreading between the left ventricular epicardium and right ventricular endocardium. Up to one-third of patients with heart failure who are eligible for cardiac resynchronisation therapy do not derive benefit from BiVP. Conduction system pacing (CSP), which includes His bundle pacing and left bundle branch area pacing, has emerged as an alternative to BiVP for cardiac resynchronisation. There is mounting evidence supporting the benefits of CSP in achieving synchronous ventricular activation and repolarisation. The aim of this review is to summarise the current options and outcomes of CSP when used for cardiac resynchronisation in patients with heart failure.
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publisher Radcliffe Medical Media
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series Arrhythmia & Electrophysiology Review
spelling doaj-art-3434d36d6fd747d996576940b2ede0f72024-12-14T16:04:37ZengRadcliffe Medical MediaArrhythmia & Electrophysiology Review2050-33692050-33772023-08-011210.15420/aer.2023.03Cardiac Resynchronisation with Conduction System PacingFatima M Ezzeddine0Isaac G Leon1Yong-Mei Cha2Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USTo date, biventricular pacing (BiVP) has been the standard pacing modality for cardiac resynchronisation therapy. However, it is non-physiological, with the activation spreading between the left ventricular epicardium and right ventricular endocardium. Up to one-third of patients with heart failure who are eligible for cardiac resynchronisation therapy do not derive benefit from BiVP. Conduction system pacing (CSP), which includes His bundle pacing and left bundle branch area pacing, has emerged as an alternative to BiVP for cardiac resynchronisation. There is mounting evidence supporting the benefits of CSP in achieving synchronous ventricular activation and repolarisation. The aim of this review is to summarise the current options and outcomes of CSP when used for cardiac resynchronisation in patients with heart failure.https://www.aerjournal.com/articleindex/aer.2023.03
spellingShingle Fatima M Ezzeddine
Isaac G Leon
Yong-Mei Cha
Cardiac Resynchronisation with Conduction System Pacing
Arrhythmia & Electrophysiology Review
title Cardiac Resynchronisation with Conduction System Pacing
title_full Cardiac Resynchronisation with Conduction System Pacing
title_fullStr Cardiac Resynchronisation with Conduction System Pacing
title_full_unstemmed Cardiac Resynchronisation with Conduction System Pacing
title_short Cardiac Resynchronisation with Conduction System Pacing
title_sort cardiac resynchronisation with conduction system pacing
url https://www.aerjournal.com/articleindex/aer.2023.03
work_keys_str_mv AT fatimamezzeddine cardiacresynchronisationwithconductionsystempacing
AT isaacgleon cardiacresynchronisationwithconductionsystempacing
AT yongmeicha cardiacresynchronisationwithconductionsystempacing