Effect of micro-osteoperforations on rate of space closure by mini-implant supported maxillary anterior en-masse retraction: A randomized clinical trial

Background: Micro-osteoperforations is one of the non-invasive surgical techniques used in attempt to accelerate OTM. Conflicting reports on its effectiveness has been reported in the literature. Objectives: The objectives of this trial were to investigate the effect of micro-osteoperforations on th...

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Main Authors: Pradeep Raghav, Amit kumar Khera, Pranav Bhasin
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Journal of Oral Biology and Craniofacial Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2212426821000105
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author Pradeep Raghav
Amit kumar Khera
Pranav Bhasin
author_facet Pradeep Raghav
Amit kumar Khera
Pranav Bhasin
author_sort Pradeep Raghav
collection DOAJ
description Background: Micro-osteoperforations is one of the non-invasive surgical techniques used in attempt to accelerate OTM. Conflicting reports on its effectiveness has been reported in the literature. Objectives: The objectives of this trial were to investigate the effect of micro-osteoperforations on the rate of space closure and on molar anchorage loss during mini-implant supported maxillary anterior en-masse retraction. Trial design: A single center, parallel arm, randomized controlled trial was conducted. Method: Sixty, male and female subjects (age range 16–25 years) having Class I bimaxillary protrusion or Class II div 1 malocclusion, who required fixed mechanotherapy with either upper 1st premolar or all four 1st premolar extractions were allocated into two groups using 1:1 allocation ratio. The allocation was done by block randomization method with a block size of 6. In the experimental group, 5 MOPs per side were performed only once just before the en-masse anterior retraction. Mini-screws were placed in order to obtain maximum anchorage. Impressions were taken every month till 4 months and rate of space closure was measured on 3D study models. Results: Data of 27 subjects in control (attrition ​= ​3) and 28 subjects in experimental group (attrition ​= ​2) were analyzed at the end of this trial. There was a statistically significant increase in the rate of en-masse retraction for the 1st month(p ​= ​0.001,95%CI, 0.17, 0.37 ​mm) but there was no statistically significant difference for the subsequent 2nd (p ​= ​0.450,95%CI,0.13,0.43 ​mm), 3rd(p ​= ​0.204,95%CI,0.23,0.47 ​mm) and 4th month (p ​= ​0.680,95%CI,0.21,0.41 ​mm) between experimental and control groups. There was also no difference (p ​> ​0.05) in molar anchorage loss between both groups at all time intervals. Conclusion: Micro-osteoperforations (MOPs) did not accelerate the rate of anterior en-masse retraction over a period of 4 months; however, it temporarily increases the rate of retraction only for first month and no affect on molar anchorage. Trial registration: The trial was registered at www.ctri.nic.in with CTRI No- CTRI/2019/03/018140).
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spelling doaj-art-3418def1d38d4c53b51c243e2da53c912024-11-23T06:28:37ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682021-04-01112185191Effect of micro-osteoperforations on rate of space closure by mini-implant supported maxillary anterior en-masse retraction: A randomized clinical trialPradeep Raghav0Amit kumar Khera1Pranav Bhasin2Department of Orthodontics, Subharti Dental College, Meerut, UP, IndiaCorresponding author. Department of Orthodontics, Subharti Dental College, Meerut, UP, India.; Department of Orthodontics, Subharti Dental College, Meerut, UP, IndiaDepartment of Orthodontics, Subharti Dental College, Meerut, UP, IndiaBackground: Micro-osteoperforations is one of the non-invasive surgical techniques used in attempt to accelerate OTM. Conflicting reports on its effectiveness has been reported in the literature. Objectives: The objectives of this trial were to investigate the effect of micro-osteoperforations on the rate of space closure and on molar anchorage loss during mini-implant supported maxillary anterior en-masse retraction. Trial design: A single center, parallel arm, randomized controlled trial was conducted. Method: Sixty, male and female subjects (age range 16–25 years) having Class I bimaxillary protrusion or Class II div 1 malocclusion, who required fixed mechanotherapy with either upper 1st premolar or all four 1st premolar extractions were allocated into two groups using 1:1 allocation ratio. The allocation was done by block randomization method with a block size of 6. In the experimental group, 5 MOPs per side were performed only once just before the en-masse anterior retraction. Mini-screws were placed in order to obtain maximum anchorage. Impressions were taken every month till 4 months and rate of space closure was measured on 3D study models. Results: Data of 27 subjects in control (attrition ​= ​3) and 28 subjects in experimental group (attrition ​= ​2) were analyzed at the end of this trial. There was a statistically significant increase in the rate of en-masse retraction for the 1st month(p ​= ​0.001,95%CI, 0.17, 0.37 ​mm) but there was no statistically significant difference for the subsequent 2nd (p ​= ​0.450,95%CI,0.13,0.43 ​mm), 3rd(p ​= ​0.204,95%CI,0.23,0.47 ​mm) and 4th month (p ​= ​0.680,95%CI,0.21,0.41 ​mm) between experimental and control groups. There was also no difference (p ​> ​0.05) in molar anchorage loss between both groups at all time intervals. Conclusion: Micro-osteoperforations (MOPs) did not accelerate the rate of anterior en-masse retraction over a period of 4 months; however, it temporarily increases the rate of retraction only for first month and no affect on molar anchorage. Trial registration: The trial was registered at www.ctri.nic.in with CTRI No- CTRI/2019/03/018140).http://www.sciencedirect.com/science/article/pii/S2212426821000105Micro osteoperforationEn-masse retractionTAD
spellingShingle Pradeep Raghav
Amit kumar Khera
Pranav Bhasin
Effect of micro-osteoperforations on rate of space closure by mini-implant supported maxillary anterior en-masse retraction: A randomized clinical trial
Journal of Oral Biology and Craniofacial Research
Micro osteoperforation
En-masse retraction
TAD
title Effect of micro-osteoperforations on rate of space closure by mini-implant supported maxillary anterior en-masse retraction: A randomized clinical trial
title_full Effect of micro-osteoperforations on rate of space closure by mini-implant supported maxillary anterior en-masse retraction: A randomized clinical trial
title_fullStr Effect of micro-osteoperforations on rate of space closure by mini-implant supported maxillary anterior en-masse retraction: A randomized clinical trial
title_full_unstemmed Effect of micro-osteoperforations on rate of space closure by mini-implant supported maxillary anterior en-masse retraction: A randomized clinical trial
title_short Effect of micro-osteoperforations on rate of space closure by mini-implant supported maxillary anterior en-masse retraction: A randomized clinical trial
title_sort effect of micro osteoperforations on rate of space closure by mini implant supported maxillary anterior en masse retraction a randomized clinical trial
topic Micro osteoperforation
En-masse retraction
TAD
url http://www.sciencedirect.com/science/article/pii/S2212426821000105
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