Crohn’s disease, irritable bowel syndrome, and chronic fatigue: the importance of communication and symptom management—a case report

Abstract Background Crohn’s disease and irritable bowel syndrome may both cause abdominal pain and diarrhea. Irritable bowel syndrome not only is an important differential diagnosis for Crohn’s disease but also occurs in one out of three patients with Crohn’s disease in remission in parallel. If not...

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Main Authors: Johannes Haedrich, Roman Huber
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Medical Case Reports
Subjects:
Online Access:https://doi.org/10.1186/s13256-024-05010-3
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author Johannes Haedrich
Roman Huber
author_facet Johannes Haedrich
Roman Huber
author_sort Johannes Haedrich
collection DOAJ
description Abstract Background Crohn’s disease and irritable bowel syndrome may both cause abdominal pain and diarrhea. Irritable bowel syndrome not only is an important differential diagnosis for Crohn’s disease but also occurs in one out of three patients with Crohn’s disease in remission in parallel. If not adequately diagnosed and treated, additional functional symptoms such as fatigue and/or muscle pain may develop, indicating a more severe course. Case presentation A 64-year-old Caucasian male with long-standing, widely inactive Crohn’s disease presented with persistent diarrhea, bloating, abdominal pain, general fatigue, unexplained hip pain, and frequent shivering with cold extremities, which had worsened following a gastrointestinal infection and psychological stress. A plausible explanation of his symptoms, based on an understanding of mind–body interactions, the autonomic nervous system, and temperature regulation, combined with symptom relief, was associated with rapid and sustainable improvement. After 2.5 years of follow-up, the patient is almost symptom-free. Conclusions This case report exemplifies the interrelation between organic (Crohn’s disease) and functional diseases (irritable bowel syndrome, chronic fatigue syndrome, and somatoform pain). It further demonstrates that these connections may be overlooked in daily practice and that providing a plausible explanation in combination with symptom relief may be important for patients with functional syndromes.
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spelling doaj-art-33e14113329f491ba7cc2bedd452c6bc2025-01-12T12:25:29ZengBMCJournal of Medical Case Reports1752-19472025-01-0119111810.1186/s13256-024-05010-3Crohn’s disease, irritable bowel syndrome, and chronic fatigue: the importance of communication and symptom management—a case reportJohannes Haedrich0Roman Huber1Center for Complementary Medicine, Department of Internal Medicine II, Faculty of Medicine, Medical Center – University of Freiburg, University of FreiburgCenter for Complementary Medicine, Department of Internal Medicine II, Faculty of Medicine, Medical Center – University of Freiburg, University of FreiburgAbstract Background Crohn’s disease and irritable bowel syndrome may both cause abdominal pain and diarrhea. Irritable bowel syndrome not only is an important differential diagnosis for Crohn’s disease but also occurs in one out of three patients with Crohn’s disease in remission in parallel. If not adequately diagnosed and treated, additional functional symptoms such as fatigue and/or muscle pain may develop, indicating a more severe course. Case presentation A 64-year-old Caucasian male with long-standing, widely inactive Crohn’s disease presented with persistent diarrhea, bloating, abdominal pain, general fatigue, unexplained hip pain, and frequent shivering with cold extremities, which had worsened following a gastrointestinal infection and psychological stress. A plausible explanation of his symptoms, based on an understanding of mind–body interactions, the autonomic nervous system, and temperature regulation, combined with symptom relief, was associated with rapid and sustainable improvement. After 2.5 years of follow-up, the patient is almost symptom-free. Conclusions This case report exemplifies the interrelation between organic (Crohn’s disease) and functional diseases (irritable bowel syndrome, chronic fatigue syndrome, and somatoform pain). It further demonstrates that these connections may be overlooked in daily practice and that providing a plausible explanation in combination with symptom relief may be important for patients with functional syndromes.https://doi.org/10.1186/s13256-024-05010-3Autonomic nervous systemGut-brain axisComplementary medicineOpiumSomatoform pain
spellingShingle Johannes Haedrich
Roman Huber
Crohn’s disease, irritable bowel syndrome, and chronic fatigue: the importance of communication and symptom management—a case report
Journal of Medical Case Reports
Autonomic nervous system
Gut-brain axis
Complementary medicine
Opium
Somatoform pain
title Crohn’s disease, irritable bowel syndrome, and chronic fatigue: the importance of communication and symptom management—a case report
title_full Crohn’s disease, irritable bowel syndrome, and chronic fatigue: the importance of communication and symptom management—a case report
title_fullStr Crohn’s disease, irritable bowel syndrome, and chronic fatigue: the importance of communication and symptom management—a case report
title_full_unstemmed Crohn’s disease, irritable bowel syndrome, and chronic fatigue: the importance of communication and symptom management—a case report
title_short Crohn’s disease, irritable bowel syndrome, and chronic fatigue: the importance of communication and symptom management—a case report
title_sort crohn s disease irritable bowel syndrome and chronic fatigue the importance of communication and symptom management a case report
topic Autonomic nervous system
Gut-brain axis
Complementary medicine
Opium
Somatoform pain
url https://doi.org/10.1186/s13256-024-05010-3
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