Long noncoding RNA Gm4419 promotes mesangial cell proliferation and extracellular matrix accumulation via the miR-455-3p/histone deacetylase 2 axis

Long noncoding RNA Gm4419 promotes mesangial cell proliferation and extracellular matrix accumulation via the miR-455-3p/histone deacetylase 2 axis

Long noncoding RNAs may function as competitive endogenous RNAs by sponging microRNAs, thereby contributing to the progression of diabetic nephropathy. In this study, a potential diabetic nephropathy-related long noncoding-microRNA-mRNA axis, Gm4419-miR-455-3p-Hdac2, was predicted using bioinformati...

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Bibliographic Details
Main Authors: Yang Wen, Hua Gan, Qing Zhong, Ying Gong
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
Subjects:
Diabetic nephropathy
Extracellular matrix
Gm4419
miR-455-3p
Histone deacetylase 2
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024148669
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