Identification of new bioactive molecules in platelet preparation, storage, and transfusion reactions for improved transfusion management

Abstract Platelet concentrates (PCs) intended for transfusion contain bioactive molecules that can be considered Biological Response Modifiers (BRMs), mainly originating from plasma regardless of the preparation process. During storage, NGAL and GDF-15 levels increase in single donor apheresis plate...

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Bibliographic Details
Main Authors: Anne-Claire Duchez, Charles-Antoine Arthaud, Marie-Ange Eyraud, Amélie Prier, Marco Heestermans, Hind Hamzeh-Cognasse, Fabrice Cognasse
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-80632-7
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