Prevalence of Surgical Site Infections Following Coronectomy: A Systematic Review and Meta-Analysis

<b>Background/Objectives:</b> This systematic review and meta-analysis aimed to investigate the prevalence of surgical site infections (SSIs) following coronectomy of mandibular third molars. <b>Methods</b>: A comprehensive literature search was conducted in Medline, Scopus,...

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Main Authors: Evangelos Kostares, Georgia Kostare, Michael Kostares, Athanasios Tsakris, Maria Kantzanou
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Dentistry Journal
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Online Access:https://www.mdpi.com/2304-6767/12/12/379
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author Evangelos Kostares
Georgia Kostare
Michael Kostares
Athanasios Tsakris
Maria Kantzanou
author_facet Evangelos Kostares
Georgia Kostare
Michael Kostares
Athanasios Tsakris
Maria Kantzanou
author_sort Evangelos Kostares
collection DOAJ
description <b>Background/Objectives:</b> This systematic review and meta-analysis aimed to investigate the prevalence of surgical site infections (SSIs) following coronectomy of mandibular third molars. <b>Methods</b>: A comprehensive literature search was conducted in Medline, Scopus, Web of Science, and Google Scholar databases up to 30 July 2024. Two independent reviewers performed study selection, data extraction, and quality assessment using the Newcastle–Ottawa Scale. Observational studies assessing SSI prevalence following coronectomy were included. The pooled prevalence of SSI with 95% confidence intervals (CI) was calculated using a random-effects model. Heterogeneity was assessed using the I<sup>2</sup> statistic, and meta-regression was conducted to explore the influence of continuous variables. <b>Results</b>: A total of 22 studies involving 2173 coronectomy procedures were included. The overall pooled prevalence of SSI was 2.4% (95% CI: 1–4.3%), with substantial heterogeneity (I<sup>2</sup> = 81%). Meta-regression showed no significant effect of the examined variables on SSI prevalence. No study was identified as a significant outlier. Quality assessments revealed that all studies had moderate methodological quality. <b>Conclusions</b>: Considerable heterogeneity was observed, likely due to variations in study settings, geographical regions, and timeframes, among other factors. Therefore, this study underscores the need for further rigorous research to better understand SSI risk factors and enhance management strategies for this postoperative complication.
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spelling doaj-art-3327d853800a4d2990604a79cf8ff7ef2024-12-27T14:20:19ZengMDPI AGDentistry Journal2304-67672024-11-01121237910.3390/dj12120379Prevalence of Surgical Site Infections Following Coronectomy: A Systematic Review and Meta-AnalysisEvangelos Kostares0Georgia Kostare1Michael Kostares2Athanasios Tsakris3Maria Kantzanou4Department of Microbiology, Medical School, National and Kapodistrian University of Athens, 115 27 Athens, GreeceDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, 115 27 Athens, GreeceDepartment of Anatomy, Medical School, National and Kapodistrian University of Athens, 115 27 Athens, GreeceDepartment of Anatomy, Medical School, National and Kapodistrian University of Athens, 115 27 Athens, GreeceDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, 115 27 Athens, Greece<b>Background/Objectives:</b> This systematic review and meta-analysis aimed to investigate the prevalence of surgical site infections (SSIs) following coronectomy of mandibular third molars. <b>Methods</b>: A comprehensive literature search was conducted in Medline, Scopus, Web of Science, and Google Scholar databases up to 30 July 2024. Two independent reviewers performed study selection, data extraction, and quality assessment using the Newcastle–Ottawa Scale. Observational studies assessing SSI prevalence following coronectomy were included. The pooled prevalence of SSI with 95% confidence intervals (CI) was calculated using a random-effects model. Heterogeneity was assessed using the I<sup>2</sup> statistic, and meta-regression was conducted to explore the influence of continuous variables. <b>Results</b>: A total of 22 studies involving 2173 coronectomy procedures were included. The overall pooled prevalence of SSI was 2.4% (95% CI: 1–4.3%), with substantial heterogeneity (I<sup>2</sup> = 81%). Meta-regression showed no significant effect of the examined variables on SSI prevalence. No study was identified as a significant outlier. Quality assessments revealed that all studies had moderate methodological quality. <b>Conclusions</b>: Considerable heterogeneity was observed, likely due to variations in study settings, geographical regions, and timeframes, among other factors. Therefore, this study underscores the need for further rigorous research to better understand SSI risk factors and enhance management strategies for this postoperative complication.https://www.mdpi.com/2304-6767/12/12/379surgical site infectionsSSImandibular third molarcoronectomyprevalencemeta-analysis
spellingShingle Evangelos Kostares
Georgia Kostare
Michael Kostares
Athanasios Tsakris
Maria Kantzanou
Prevalence of Surgical Site Infections Following Coronectomy: A Systematic Review and Meta-Analysis
Dentistry Journal
surgical site infections
SSI
mandibular third molar
coronectomy
prevalence
meta-analysis
title Prevalence of Surgical Site Infections Following Coronectomy: A Systematic Review and Meta-Analysis
title_full Prevalence of Surgical Site Infections Following Coronectomy: A Systematic Review and Meta-Analysis
title_fullStr Prevalence of Surgical Site Infections Following Coronectomy: A Systematic Review and Meta-Analysis
title_full_unstemmed Prevalence of Surgical Site Infections Following Coronectomy: A Systematic Review and Meta-Analysis
title_short Prevalence of Surgical Site Infections Following Coronectomy: A Systematic Review and Meta-Analysis
title_sort prevalence of surgical site infections following coronectomy a systematic review and meta analysis
topic surgical site infections
SSI
mandibular third molar
coronectomy
prevalence
meta-analysis
url https://www.mdpi.com/2304-6767/12/12/379
work_keys_str_mv AT evangeloskostares prevalenceofsurgicalsiteinfectionsfollowingcoronectomyasystematicreviewandmetaanalysis
AT georgiakostare prevalenceofsurgicalsiteinfectionsfollowingcoronectomyasystematicreviewandmetaanalysis
AT michaelkostares prevalenceofsurgicalsiteinfectionsfollowingcoronectomyasystematicreviewandmetaanalysis
AT athanasiostsakris prevalenceofsurgicalsiteinfectionsfollowingcoronectomyasystematicreviewandmetaanalysis
AT mariakantzanou prevalenceofsurgicalsiteinfectionsfollowingcoronectomyasystematicreviewandmetaanalysis