In Vivo Monitoring of Pancreatic β-Cells in a Transgenic Mouse Model
We generated a transgenic mouse model ( RIP-luc ) for the in vivo monitoring of pancreatic islet mass and function in response to metabolic disease. Using the rat insulin promoter fused to firefly luciferase, and noninvasive technology to detect luciferase activity, we tracked changes in reporter si...
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Main Authors: | Steven J. Smith, Hongbing Zhang, Anne O. Clermont, Alvin C. Powers, Dixon B. Kaufman, Anthony F. Purchio, David B. West |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2006-04-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2006.00007 |
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