hUC-MSC extracellular vesicles protect against hypoxic-ischemic brain injury by promoting NLRP3 ubiquitination

hUC-MSC extracellular vesicles protect against hypoxic-ischemic brain injury by promoting NLRP3 ubiquitination

Hypoxic-ischemic brain injury (HIBD) is a major cause of neonatal mortality and long-term neurological deficits, with limited treatment options. Extracellular vesicles (EVs) from human umbilical cord mesenchymal stem cells (hUC-MSC-EVs) have shown promise in neuroprotection, but the mechanisms remai...

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Bibliographic Details
Main Authors: Shanshan Xiao, Ying Lv, Xuejing Hou, Shuqiang Qu
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2024-12-01
Series:Biomolecules & Biomedicine
Subjects:
Mesenchymal stem cells
MSCs
extracellular vesicles
EVs
hypoxia-ischemia
HI
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/10706
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