SARS-CoV-2 and influenza vaccine hesitancy during the COVID-19 pandemic in a dynamic perspective

To investigate the dynamic evolution of vaccine hesitancy toward both COVID-19 and influenza in a context characterized by the compresence of SARS-CoV-2 pandemic and seasonal flu epidemics, a two times repeated cross-sectional exploratory design was performed at Udine Hospital (Italy) following a co...

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Main Authors: Valentina Gerussi, Maddalena Peghin, Alvisa Palese, Maria De Martino, Elena Graziano, Stefania Chiappinotto, Federico Fonda, Giulia Bontempo, Tosca Semenzin, Luca Martini, Miriam Isola, Carlo Tascini
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Human Vaccines & Immunotherapeutics
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Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2024.2358565
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author Valentina Gerussi
Maddalena Peghin
Alvisa Palese
Maria De Martino
Elena Graziano
Stefania Chiappinotto
Federico Fonda
Giulia Bontempo
Tosca Semenzin
Luca Martini
Miriam Isola
Carlo Tascini
author_facet Valentina Gerussi
Maddalena Peghin
Alvisa Palese
Maria De Martino
Elena Graziano
Stefania Chiappinotto
Federico Fonda
Giulia Bontempo
Tosca Semenzin
Luca Martini
Miriam Isola
Carlo Tascini
author_sort Valentina Gerussi
collection DOAJ
description To investigate the dynamic evolution of vaccine hesitancy toward both COVID-19 and influenza in a context characterized by the compresence of SARS-CoV-2 pandemic and seasonal flu epidemics, a two times repeated cross-sectional exploratory design was performed at Udine Hospital (Italy) following a cohort of 479 adult patients with a previous history of SARS-CoV-2 infection in 2020. Vaccine attitude was assessed through standardized telephone interviews performed at 12 and 18 months after the acute illness. The first interview reported the success of the 2020/21 seasonal influenza immunization with 46.8% (224/479) of the participants showing a positive attitude, especially the elderly and people with comorbidities (p < .001), but the investigation conducted at 18 months showed a drastic drop in flu shot acceptance (30/166, 18.1%). On the other hand, a great increase in vaccinations against SARS-CoV-2 occurred after the introduction of Green Pass (26.7% vs 72.9%). The major drivers of flu vaccine skepticism were represented by the feeling of protection regardless of prevention and by concerns regarding vaccines safety and efficacy; conversely compulsory strategies seemed to play a secondary role, since only a minority of the participants identified in the restrictions induced by the certification the major incentive to get immunized against SARS-CoV-2. The focus on this peculiar historical period helps to take a step forward in the comprehension of the complexity and dynamicity of the vaccine hesitancy phenomenon. Future vaccination campaigns will need to consider the role of personal opinions and emotions, interpreted according to the social and political context.
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spelling doaj-art-329e37b51f454131b05daf06b4a255ad2025-08-20T03:12:43ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2024-12-0120110.1080/21645515.2024.2358565SARS-CoV-2 and influenza vaccine hesitancy during the COVID-19 pandemic in a dynamic perspectiveValentina Gerussi0Maddalena Peghin1Alvisa Palese2Maria De Martino3Elena Graziano4Stefania Chiappinotto5Federico Fonda6Giulia Bontempo7Tosca Semenzin8Luca Martini9Miriam Isola10Carlo Tascini11Infectious Diseases Division, Santa Maria Misericordia University Hospital, Udine, ItalyInfectious and Tropical Diseases Unit, Department of Medicine and Surgery, University of Insubria-ASST-Sette Laghi, Varese, ItalyDepartment of Medicine, School of Nursing, University of Udine, Udine, ItalyDepartment of Medicine, Institute of Statistics, University of Udine, Udine, ItalyInfectious and Tropical Diseases Unit, Department of Medicine and Surgery, University of Insubria-ASST-Sette Laghi, Varese, ItalyDepartment of Medicine, School of Nursing, University of Udine, Udine, ItalyDepartment of Medicine, School of Nursing, University of Udine, Udine, ItalyInfectious Diseases Division, Santa Maria Misericordia University Hospital, Udine, ItalyInfectious Diseases Division, Santa Maria Misericordia University Hospital, Udine, ItalyInfectious Diseases Division, Santa Maria Misericordia University Hospital, Udine, ItalyDepartment of Medicine, Institute of Statistics, University of Udine, Udine, ItalyInfectious Diseases Division, Santa Maria Misericordia University Hospital, Udine, ItalyTo investigate the dynamic evolution of vaccine hesitancy toward both COVID-19 and influenza in a context characterized by the compresence of SARS-CoV-2 pandemic and seasonal flu epidemics, a two times repeated cross-sectional exploratory design was performed at Udine Hospital (Italy) following a cohort of 479 adult patients with a previous history of SARS-CoV-2 infection in 2020. Vaccine attitude was assessed through standardized telephone interviews performed at 12 and 18 months after the acute illness. The first interview reported the success of the 2020/21 seasonal influenza immunization with 46.8% (224/479) of the participants showing a positive attitude, especially the elderly and people with comorbidities (p < .001), but the investigation conducted at 18 months showed a drastic drop in flu shot acceptance (30/166, 18.1%). On the other hand, a great increase in vaccinations against SARS-CoV-2 occurred after the introduction of Green Pass (26.7% vs 72.9%). The major drivers of flu vaccine skepticism were represented by the feeling of protection regardless of prevention and by concerns regarding vaccines safety and efficacy; conversely compulsory strategies seemed to play a secondary role, since only a minority of the participants identified in the restrictions induced by the certification the major incentive to get immunized against SARS-CoV-2. The focus on this peculiar historical period helps to take a step forward in the comprehension of the complexity and dynamicity of the vaccine hesitancy phenomenon. Future vaccination campaigns will need to consider the role of personal opinions and emotions, interpreted according to the social and political context.https://www.tandfonline.com/doi/10.1080/21645515.2024.2358565InfluenzaCOVID-19SARS-CoV-2Green-Passvaccinationvaccine-hesitancy
spellingShingle Valentina Gerussi
Maddalena Peghin
Alvisa Palese
Maria De Martino
Elena Graziano
Stefania Chiappinotto
Federico Fonda
Giulia Bontempo
Tosca Semenzin
Luca Martini
Miriam Isola
Carlo Tascini
SARS-CoV-2 and influenza vaccine hesitancy during the COVID-19 pandemic in a dynamic perspective
Human Vaccines & Immunotherapeutics
Influenza
COVID-19
SARS-CoV-2
Green-Pass
vaccination
vaccine-hesitancy
title SARS-CoV-2 and influenza vaccine hesitancy during the COVID-19 pandemic in a dynamic perspective
title_full SARS-CoV-2 and influenza vaccine hesitancy during the COVID-19 pandemic in a dynamic perspective
title_fullStr SARS-CoV-2 and influenza vaccine hesitancy during the COVID-19 pandemic in a dynamic perspective
title_full_unstemmed SARS-CoV-2 and influenza vaccine hesitancy during the COVID-19 pandemic in a dynamic perspective
title_short SARS-CoV-2 and influenza vaccine hesitancy during the COVID-19 pandemic in a dynamic perspective
title_sort sars cov 2 and influenza vaccine hesitancy during the covid 19 pandemic in a dynamic perspective
topic Influenza
COVID-19
SARS-CoV-2
Green-Pass
vaccination
vaccine-hesitancy
url https://www.tandfonline.com/doi/10.1080/21645515.2024.2358565
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