Immune cell senescence in autoimmunity: implications for disease pathogenesis and therapeutic targeting

The senescence of immune cells has also emerged as a key hallmark of immunological dysregulation and chronic inflammation in autoimmunity. Senescent immune cells are irreversibly arrested in the cell cycle, exhibit antimetabolic characteristics, and secrete pro-inflammatory mediators, all together d...

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Bibliographic Details
Main Authors: Fei Yin, Yangfang He, Jian Li, Yuan Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1596686/full
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