Use of bitter melon seed oil (Momordica Charantia) to Improve the photoprotective effect of Sunscreen Formulations
Bitter melon seed oil (BMSO) was identified as having potential as an anti-UV radiation agent due to alpha-oleo stearic acid, flavonoids, tannins, polyphenols, and phytosterols, which have the potential as antioxidants. Antioxidants are the main protection for the skin from the dangers of solar rad...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universitas Ahmad Dahlan
2024-11-01
|
| Series: | Pharmaciana |
| Subjects: | |
| Online Access: | https://journal.uad.ac.id/index.php/PHARMACIANA/article/view/28208 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841545644260458496 |
|---|---|
| author | Lina Winarti Ema Prastiwi Refayani |
| author_facet | Lina Winarti Ema Prastiwi Refayani |
| author_sort | Lina Winarti |
| collection | DOAJ |
| description |
Bitter melon seed oil (BMSO) was identified as having potential as an anti-UV radiation agent due to alpha-oleo stearic acid, flavonoids, tannins, polyphenols, and phytosterols, which have the potential as antioxidants. Antioxidants are the main protection for the skin from the dangers of solar radiation, making BMSO a good quality if developed in sunscreen cream. This research aims to determine the effect of adding variations in the concentration of BMSO on the physical characteristics and in vitro photoprotective effectiveness of cream of oxybenzone and octyl methoxycinnamate. Sunscreen creams are made with each BMSO concentration of 0%, 6%, 8%, 10%, and 12%. The result shows that the greater the concentration of BMSO added, the lower the viscosity and pH values, the spreadability and SPF (sun protection factor) values of the cream increase, and the %TP (percentage of transmission pigmentation) and %TE (percentage of transmission erythema) become smaller. The best formula is the formula that contains the highest concentration of BMSO (12%). The characteristics of the best formula are a slightly yellowish, soft cream appearance and a slight smell typical of bitter melon. The spreadability value of the best formula cream is 6.6 ± 0.1 cm, pH of 6.57 ± 0.01, and viscosity of 88.3 ± 4.1 dPa.s, SPF value of 24.27 ± 0.28, %TE of 0.931 ±0.084, and %TP of 0.981±0.0001. These results show that BMSO has the potential to be an active ingredient in sunscreen to reduce the negative effects of using synthetic sunscreen, such as allergenic and irritant.
|
| format | Article |
| id | doaj-art-327d95b61dff46f6ab24d1b6a3fb2c2d |
| institution | Kabale University |
| issn | 2088-4559 2477-0256 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Universitas Ahmad Dahlan |
| record_format | Article |
| series | Pharmaciana |
| spelling | doaj-art-327d95b61dff46f6ab24d1b6a3fb2c2d2025-01-12T00:37:09ZengUniversitas Ahmad DahlanPharmaciana2088-45592477-02562024-11-0114310.12928/pharmaciana.v14i3.2820820346Use of bitter melon seed oil (Momordica Charantia) to Improve the photoprotective effect of Sunscreen FormulationsLina Winarti0Ema Prastiwi Refayani 1Universitas JemberUniversity of Jember Bitter melon seed oil (BMSO) was identified as having potential as an anti-UV radiation agent due to alpha-oleo stearic acid, flavonoids, tannins, polyphenols, and phytosterols, which have the potential as antioxidants. Antioxidants are the main protection for the skin from the dangers of solar radiation, making BMSO a good quality if developed in sunscreen cream. This research aims to determine the effect of adding variations in the concentration of BMSO on the physical characteristics and in vitro photoprotective effectiveness of cream of oxybenzone and octyl methoxycinnamate. Sunscreen creams are made with each BMSO concentration of 0%, 6%, 8%, 10%, and 12%. The result shows that the greater the concentration of BMSO added, the lower the viscosity and pH values, the spreadability and SPF (sun protection factor) values of the cream increase, and the %TP (percentage of transmission pigmentation) and %TE (percentage of transmission erythema) become smaller. The best formula is the formula that contains the highest concentration of BMSO (12%). The characteristics of the best formula are a slightly yellowish, soft cream appearance and a slight smell typical of bitter melon. The spreadability value of the best formula cream is 6.6 ± 0.1 cm, pH of 6.57 ± 0.01, and viscosity of 88.3 ± 4.1 dPa.s, SPF value of 24.27 ± 0.28, %TE of 0.931 ±0.084, and %TP of 0.981±0.0001. These results show that BMSO has the potential to be an active ingredient in sunscreen to reduce the negative effects of using synthetic sunscreen, such as allergenic and irritant. https://journal.uad.ac.id/index.php/PHARMACIANA/article/view/28208BMSOoxybenzoneoctyl metoxycinamatessunscreen |
| spellingShingle | Lina Winarti Ema Prastiwi Refayani Use of bitter melon seed oil (Momordica Charantia) to Improve the photoprotective effect of Sunscreen Formulations Pharmaciana BMSO oxybenzone octyl metoxycinamates sunscreen |
| title | Use of bitter melon seed oil (Momordica Charantia) to Improve the photoprotective effect of Sunscreen Formulations |
| title_full | Use of bitter melon seed oil (Momordica Charantia) to Improve the photoprotective effect of Sunscreen Formulations |
| title_fullStr | Use of bitter melon seed oil (Momordica Charantia) to Improve the photoprotective effect of Sunscreen Formulations |
| title_full_unstemmed | Use of bitter melon seed oil (Momordica Charantia) to Improve the photoprotective effect of Sunscreen Formulations |
| title_short | Use of bitter melon seed oil (Momordica Charantia) to Improve the photoprotective effect of Sunscreen Formulations |
| title_sort | use of bitter melon seed oil momordica charantia to improve the photoprotective effect of sunscreen formulations |
| topic | BMSO oxybenzone octyl metoxycinamates sunscreen |
| url | https://journal.uad.ac.id/index.php/PHARMACIANA/article/view/28208 |
| work_keys_str_mv | AT linawinarti useofbittermelonseedoilmomordicacharantiatoimprovethephotoprotectiveeffectofsunscreenformulations AT emaprastiwirefayani useofbittermelonseedoilmomordicacharantiatoimprovethephotoprotectiveeffectofsunscreenformulations |