Piezo1 overexpression in the uterus contributes to myometrium contraction and inflammation-associated preterm birth

Piezo1 overexpression in the uterus contributes to myometrium contraction and inflammation-associated preterm birth

Abstract Background Preterm birth, a leading cause of perinatal mortality and morbidity, is often associated with inflammation and aberrant myometrial contractions. This study investigates the role of Piezo1, a mechanosensitive ion channel, in myometrium contraction and inflammation-associated prete...

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Bibliographic Details
Main Authors: Yanmei Bi, Hao Li, Min Diao, Qian Liu, Lu Huang, Yunkai Tao, Yantong Wan, Xuemei Lin
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Translational Medicine
Subjects:
Preterm birth
Piezo1
Mechanosensitive ion channels
Myometrium contraction
Online Access:https://doi.org/10.1186/s12967-024-05978-y
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