Extracellular vesicles as biomarkers for traumatic brain injury using a 3D in vitro human brain tissue model

Extracellular vesicles as biomarkers for traumatic brain injury using a 3D in vitro human brain tissue model

Abstract Traumatic brain injury (TBI) is a significant health challenge worldwide, with current diagnostics and treatment falling short due to the complex pathophysiology involved. Extracellular vesicles (EVs) play a crucial role in brain injury response and are promising biomarkers for understandin...

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Bibliographic Details
Main Authors: Peter Hsi, Vishal Tandon, David L. Kaplan
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Extracellular vesicles
Traumatic brain injury
MicroRNA
Brain model
Biomarkers
Tissue engineering
Online Access:https://doi.org/10.1038/s41598-025-04835-2
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