基于临床特征、SPECT/CT脑灌注显像参数和颈动脉超声斑块特征的多因素模型对无症状性颈动脉狭窄患者认知功能下降的风险评估(Risk Assessment of Cognitive Decline in Asymptomatic Carotid Artery Stenosis Patients: A Multifactor Model Based on Clinical Features, SPECT/CT Cerebral Perfusion Imaging Parameters, and Carotid Ultrasound Plaque Characteristics)

基于临床特征、SPECT/CT脑灌注显像参数和颈动脉超声斑块特征的多因素模型对无症状性颈动脉狭窄患者认知功能下降的风险评估(Risk Assessment of Cognitive Decline in Asymptomatic Carotid Artery Stenosis Patients: A Multifactor Model Based on Clinical Features, SPECT/CT Cerebral Perfusion Imaging Parameters, and Carotid Ultrasound Plaque Characteristics)

目的 构建一个整合临床特征、SPECT/CT脑灌注显像参数和颈动脉超声斑块特征的多因素预测模型，用于评估无症状性颈动脉狭窄患者的认知功能下降风险。 方法 回顾性分析2021年1月1日—2022年12月31日在山东第二医科大学附属医院就诊的无症状性颈动脉狭窄患者，所有患者在就诊时均完成以下评估：采用SPECT/CT脑灌注显像评估全脑平均局部脑血流量（regional cerebral blood flow，rCBF），通过颈动脉超声检查评估斑块面积及回声特征，使用MoCA进行认知功能评估并在随访1年后评估认知功能变化。以1年随访期间MoCA评分下降2分或以上为认知功能下降，将患者分为认知功能下...

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Main Author: 王梦蝶，韩硕，刘志翔，谢海(WANG Mengdie, HAN Shuo, LIU Zhixiang, XIE Hai)
Format: Article
Language:zho
Published: Editorial Department of Chinese Journal of Stroke 2025-07-01
Series:Zhongguo cuzhong zazhi
Subjects:
颈动脉狭窄
认知功能下降
spect/ct脑灌注显像
颈动脉超声
预测模型
carotid artery stenosis
cognitive decline
spect/ct cerebral perfusion imaging
carotid ultrasound
prediction model
Online Access:https://www.chinastroke.org.cn/CN/10.3969/j.issn.1673-5765.2025.07.007
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https://www.chinastroke.org.cn/CN/10.3969/j.issn.1673-5765.2025.07.007

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