AdipoR1 enhances the radiation resistance via ESR1/CCNB1IP1/cyclin B1 pathway in hepatocellular carcinoma cells

AdipoR1 enhances the radiation resistance via ESR1/CCNB1IP1/cyclin B1 pathway in hepatocellular carcinoma cells

Abstract Hepatocellular carcinoma is one of the most common malignant tumors, and radiotherapy plays a pivotal role in its therapeutic regimen. However, radiotherapy resistance is the main cause of therapeutic failure in patients. Our previous study revealed that Adiponectin Receptor 1 (AdipoR1) is...

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Bibliographic Details
Main Authors: Yuhan Gan, Linhui Zhu, Yimo Li, Ruoting Ge, Jiahe Tian, Yuxin Chen, Xiang He, Shumei Ma, Xiaodong Liu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Medicine
Subjects:
HCC
AdipoR1
Radiation resistance
Cell cycle
Cyclin B1
CCNB1IP1
Online Access:https://doi.org/10.1186/s10020-025-01065-0
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