A General Strategy to Fine‐Tune Group 14 Rhodamines for Ultrahigh Signal‐to‐Noise Ratio Labeling In Vivo by Nano‐Aggregation

A General Strategy to Fine‐Tune Group 14 Rhodamines for Ultrahigh Signal‐to‐Noise Ratio Labeling In Vivo by Nano‐Aggregation

ABSTRACT Ultrahigh signal‐to‐noise ratio (SNR) labeling enables precise visualization of biological structures in vivo. We boosted fluorogenicity in group‐14‐rhodamines by comprehensively manipulating their dynamics in physical (aggregate/monomer, KA/M) and chemical (closed/open spirolactone, KC/O)...

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Bibliographic Details
Main Authors: Ning Wang, Ting Wang, Mengting Fan, Chen Li, Yue Tian, Xiaoyan Cui
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Aggregate
Subjects:
fluorescence imaging
nano‐aggregates
signal‐to‐noise ratio
substituted rhodamine
super‐resolution microscopy
Online Access:https://doi.org/10.1002/agt2.70077
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https://doi.org/10.1002/agt2.70077

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