A Retrospective Analysis of Crayfish-Related Rhabdomyolysis (Haff Disease)

Objective. To investigate the epidemiologic and etiologic factors, clinical features, therapeutic regimen, and prognosis of crayfish-related rhabdomyolysis (Haff disease). Methods. Retrospectively analyzed the clinical data of 29 patients with crayfish-related rhabdomyolysis (Haff disease) from July...

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Main Authors: Changbao Huang, Liangfei Peng, Nengkai Gong, Cheng Xue, Weihua Wang, Jinghan Jiang
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Emergency Medicine International
Online Access:http://dx.doi.org/10.1155/2019/4209745
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author Changbao Huang
Liangfei Peng
Nengkai Gong
Cheng Xue
Weihua Wang
Jinghan Jiang
author_facet Changbao Huang
Liangfei Peng
Nengkai Gong
Cheng Xue
Weihua Wang
Jinghan Jiang
author_sort Changbao Huang
collection DOAJ
description Objective. To investigate the epidemiologic and etiologic factors, clinical features, therapeutic regimen, and prognosis of crayfish-related rhabdomyolysis (Haff disease). Methods. Retrospectively analyzed the clinical data of 29 patients with crayfish-related rhabdomyolysis (Haff disease) from July to August 2016, summarized the clinical characteristics, and evaluated the prognosis. Results. Clinical data of a total of 29 cases of Haff disease were retrospectively analyzed. The disease onset occurred after consumption of cooked crayfish with the incubation period ranging from 1 h to 48 h. There were no gender differences and significantly elevated CK in the duration with peak value of 41575.0U/L; the median value was 2445.0U/L (range: from 1187.0 U/L to 4722.0 U/L) and there was coincident elevated CK-MB. There was also no hepatorenal damage and transient urinalysis was abnormal. The most common presenting symptoms were myalgia (100%), weakness and numbness (51.7%), chest tightness and chest pain (41.4%), back pain (41.4%), and extremities pain (37.9%). All the patients recovered and no patients died. Conclusions. Crayfish-related rhabdomyolysis (Haff disease) is a kind of a case or cluster of patients present with severe myalgia or weakness of unknown etiology and mechanism disease; however, the clinical signs and symptoms are relatively mild with favorable outcome.
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spelling doaj-art-31b569b5c49c4f32b3df5f82c1e4fbe62025-08-20T03:55:00ZengWileyEmergency Medicine International2090-28402090-28592019-01-01201910.1155/2019/42097454209745A Retrospective Analysis of Crayfish-Related Rhabdomyolysis (Haff Disease)Changbao Huang0Liangfei Peng1Nengkai Gong2Cheng Xue3Weihua Wang4Jinghan Jiang5Department of Emergency Medicine, Yijishan Hospital, Wannan Medical College, Wuhu, Anhui 241001, ChinaDepartment of Emergency Medicine, Yijishan Hospital, Wannan Medical College, Wuhu, Anhui 241001, ChinaDepartment of Emergency Medicine, Yijishan Hospital, Wannan Medical College, Wuhu, Anhui 241001, ChinaDepartment of Emergency Medicine, Yijishan Hospital, Wannan Medical College, Wuhu, Anhui 241001, ChinaDepartment of Emergency Medicine, Yijishan Hospital, Wannan Medical College, Wuhu, Anhui 241001, ChinaDepartment of Emergency Medicine, Yijishan Hospital, Wannan Medical College, Wuhu, Anhui 241001, ChinaObjective. To investigate the epidemiologic and etiologic factors, clinical features, therapeutic regimen, and prognosis of crayfish-related rhabdomyolysis (Haff disease). Methods. Retrospectively analyzed the clinical data of 29 patients with crayfish-related rhabdomyolysis (Haff disease) from July to August 2016, summarized the clinical characteristics, and evaluated the prognosis. Results. Clinical data of a total of 29 cases of Haff disease were retrospectively analyzed. The disease onset occurred after consumption of cooked crayfish with the incubation period ranging from 1 h to 48 h. There were no gender differences and significantly elevated CK in the duration with peak value of 41575.0U/L; the median value was 2445.0U/L (range: from 1187.0 U/L to 4722.0 U/L) and there was coincident elevated CK-MB. There was also no hepatorenal damage and transient urinalysis was abnormal. The most common presenting symptoms were myalgia (100%), weakness and numbness (51.7%), chest tightness and chest pain (41.4%), back pain (41.4%), and extremities pain (37.9%). All the patients recovered and no patients died. Conclusions. Crayfish-related rhabdomyolysis (Haff disease) is a kind of a case or cluster of patients present with severe myalgia or weakness of unknown etiology and mechanism disease; however, the clinical signs and symptoms are relatively mild with favorable outcome.http://dx.doi.org/10.1155/2019/4209745
spellingShingle Changbao Huang
Liangfei Peng
Nengkai Gong
Cheng Xue
Weihua Wang
Jinghan Jiang
A Retrospective Analysis of Crayfish-Related Rhabdomyolysis (Haff Disease)
Emergency Medicine International
title A Retrospective Analysis of Crayfish-Related Rhabdomyolysis (Haff Disease)
title_full A Retrospective Analysis of Crayfish-Related Rhabdomyolysis (Haff Disease)
title_fullStr A Retrospective Analysis of Crayfish-Related Rhabdomyolysis (Haff Disease)
title_full_unstemmed A Retrospective Analysis of Crayfish-Related Rhabdomyolysis (Haff Disease)
title_short A Retrospective Analysis of Crayfish-Related Rhabdomyolysis (Haff Disease)
title_sort retrospective analysis of crayfish related rhabdomyolysis haff disease
url http://dx.doi.org/10.1155/2019/4209745
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