Assessment of Proximate, Vitamins, In Vitro Antioxidant, and Functional Properties of Some Polyherbal Formulations as Prospective Botanical Candidates for Pharmaceutical Applications
Study’s Novelty/Excerpt • This study evaluates the combined effects of Turmeric, Coriander, and Mint (TCM) leaves on nutritional, functional, and antioxidant properties in polyherbal formulations, showing their superior glucose absorption capacity and antioxidant activity compared to single herb...
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| Format: | Article |
| Language: | English |
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Umaru Musa Yar'adua University, Katsina, Nigeria
2024-06-01
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| Series: | UMYU Journal of Microbiology Research |
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| Online Access: | https://ujmr.umyu.edu.ng/index.php/ujmr/article/view/633 |
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| author | Abubakar Mannir Rawayau Aliyu Sani Yandoma F Lawal Muhammad Nasir Rufa'i Ahmed Sani A Halliru |
| author_facet | Abubakar Mannir Rawayau Aliyu Sani Yandoma F Lawal Muhammad Nasir Rufa'i Ahmed Sani A Halliru |
| author_sort | Abubakar Mannir Rawayau |
| collection | DOAJ |
| description | Study’s Novelty/Excerpt
• This study evaluates the combined effects of Turmeric, Coriander, and Mint (TCM) leaves on nutritional, functional, and antioxidant properties in polyherbal formulations, showing their superior glucose absorption capacity and antioxidant activity compared to single herbs.
• The research highlights a significant nutritional shift in the TCM formulation, providing evidence for its enhanced efficacy in nutraceutical applications.
• These findings show the potential of TCM as a novel botanical candidate for safe and effective pharmaceutical development.
Full Abstract
Conventional drugs have numerous side effects, toxicity, and microbial resistance, making them unsafe for consumption. Polyherbal formulations are popular due to their potency, low cost, clinical efficacy, safety, and success in chronic conditions. The study aims to evaluate the proximate, vitamin, functional, and antioxidant activity of polyherbal formulations of Turmeric, Coriander, and mint (TCM) leaves as potential botanical candidates for pharmaceutical screening. Thus, addressing these issues and improving access to drugs for individuals by focusing on polyherbal formulations (PHF) is a potential solution. All analyses conducted were determined according to standard assay guidelines. The proximate analysis shows no significant difference among the formulations (p > 0.05), with TCM showing a nutritional profile shift because of the combination of the herbs rather than single herbs. In the vitamin composition, Vitamin A displays a pattern among the formulations, with TC and CM showing higher values than TM and TCM, which are, in turn, better than the single herbs. Vitamin C fluctuates across the formulations. TM displays higher, while T shows the lowest. Vitamin E content remains relatively stable among the formulations with a difference from the single herbs. In the functional properties, GAC displays notable variations among the formulations. TCM exhibits the highest GAC at 14.7 %, indicating its superior ability to absorb glucose. TC, CM, TM, and the single herbs show a comparatively lower GAC value. WAC also varies among the formulations. TCM displays lower WAC compared to TC, TM and CM. The single herbs show the lowest WAC. OAC shows intriguing trends across the formulations. TCM and TC exhibit similar OAC, while CM shows a slightly higher OAC, and TM displays better than single herbs, showing no significant difference (p > 0.05). In the antioxidant Activity, TCM shows lightly higher scavenging activity in 40, 80 and 120 mg/mL concentrations than other formulations. The outcome of this study has led us to conclude that employing safe combinations of these herbal formulations for the production of nutraceuticals is recommended. |
| format | Article |
| id | doaj-art-31993c8b5d04406f96cf2d40f9528a00 |
| institution | Kabale University |
| issn | 2616-0668 2814-1822 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Umaru Musa Yar'adua University, Katsina, Nigeria |
| record_format | Article |
| series | UMYU Journal of Microbiology Research |
| spelling | doaj-art-31993c8b5d04406f96cf2d40f9528a002024-11-27T17:02:16ZengUmaru Musa Yar'adua University, Katsina, NigeriaUMYU Journal of Microbiology Research2616-06682814-18222024-06-0146447410.47430/ujmr.2493.054633Assessment of Proximate, Vitamins, In Vitro Antioxidant, and Functional Properties of Some Polyherbal Formulations as Prospective Botanical Candidates for Pharmaceutical ApplicationsAbubakar Mannir Rawayau0https://orcid.org/0009-0001-1260-8334Aliyu Sani Yandoma1F Lawal Muhammad2Nasir Rufa'i3Ahmed Sani4A Halliru5Biochemistry Department, Umaru Musa Yaradua University Katsina, NigeriaBiochemistry Department, Umaru Musa Yaradua University Katsina, NigeriaBiochemistry Department, Umaru Musa Yaradua University Katsina, NigeriaBiochemistry Department, Umaru Musa Yaradua University Katsina, NigeriaFederal Teaching Hospital Katsina, NigeriaCherish College of Nursing and Midwifery Batsari, Katsina, NigeriaStudy’s Novelty/Excerpt • This study evaluates the combined effects of Turmeric, Coriander, and Mint (TCM) leaves on nutritional, functional, and antioxidant properties in polyherbal formulations, showing their superior glucose absorption capacity and antioxidant activity compared to single herbs. • The research highlights a significant nutritional shift in the TCM formulation, providing evidence for its enhanced efficacy in nutraceutical applications. • These findings show the potential of TCM as a novel botanical candidate for safe and effective pharmaceutical development. Full Abstract Conventional drugs have numerous side effects, toxicity, and microbial resistance, making them unsafe for consumption. Polyherbal formulations are popular due to their potency, low cost, clinical efficacy, safety, and success in chronic conditions. The study aims to evaluate the proximate, vitamin, functional, and antioxidant activity of polyherbal formulations of Turmeric, Coriander, and mint (TCM) leaves as potential botanical candidates for pharmaceutical screening. Thus, addressing these issues and improving access to drugs for individuals by focusing on polyherbal formulations (PHF) is a potential solution. All analyses conducted were determined according to standard assay guidelines. The proximate analysis shows no significant difference among the formulations (p > 0.05), with TCM showing a nutritional profile shift because of the combination of the herbs rather than single herbs. In the vitamin composition, Vitamin A displays a pattern among the formulations, with TC and CM showing higher values than TM and TCM, which are, in turn, better than the single herbs. Vitamin C fluctuates across the formulations. TM displays higher, while T shows the lowest. Vitamin E content remains relatively stable among the formulations with a difference from the single herbs. In the functional properties, GAC displays notable variations among the formulations. TCM exhibits the highest GAC at 14.7 %, indicating its superior ability to absorb glucose. TC, CM, TM, and the single herbs show a comparatively lower GAC value. WAC also varies among the formulations. TCM displays lower WAC compared to TC, TM and CM. The single herbs show the lowest WAC. OAC shows intriguing trends across the formulations. TCM and TC exhibit similar OAC, while CM shows a slightly higher OAC, and TM displays better than single herbs, showing no significant difference (p > 0.05). In the antioxidant Activity, TCM shows lightly higher scavenging activity in 40, 80 and 120 mg/mL concentrations than other formulations. The outcome of this study has led us to conclude that employing safe combinations of these herbal formulations for the production of nutraceuticals is recommended.https://ujmr.umyu.edu.ng/index.php/ujmr/article/view/633turmericcoriander and mint leavespolyherbal formulationproximatevitamins |
| spellingShingle | Abubakar Mannir Rawayau Aliyu Sani Yandoma F Lawal Muhammad Nasir Rufa'i Ahmed Sani A Halliru Assessment of Proximate, Vitamins, In Vitro Antioxidant, and Functional Properties of Some Polyherbal Formulations as Prospective Botanical Candidates for Pharmaceutical Applications UMYU Journal of Microbiology Research turmeric coriander and mint leaves polyherbal formulation proximate vitamins |
| title | Assessment of Proximate, Vitamins, In Vitro Antioxidant, and Functional Properties of Some Polyherbal Formulations as Prospective Botanical Candidates for Pharmaceutical Applications |
| title_full | Assessment of Proximate, Vitamins, In Vitro Antioxidant, and Functional Properties of Some Polyherbal Formulations as Prospective Botanical Candidates for Pharmaceutical Applications |
| title_fullStr | Assessment of Proximate, Vitamins, In Vitro Antioxidant, and Functional Properties of Some Polyherbal Formulations as Prospective Botanical Candidates for Pharmaceutical Applications |
| title_full_unstemmed | Assessment of Proximate, Vitamins, In Vitro Antioxidant, and Functional Properties of Some Polyherbal Formulations as Prospective Botanical Candidates for Pharmaceutical Applications |
| title_short | Assessment of Proximate, Vitamins, In Vitro Antioxidant, and Functional Properties of Some Polyherbal Formulations as Prospective Botanical Candidates for Pharmaceutical Applications |
| title_sort | assessment of proximate vitamins in vitro antioxidant and functional properties of some polyherbal formulations as prospective botanical candidates for pharmaceutical applications |
| topic | turmeric coriander and mint leaves polyherbal formulation proximate vitamins |
| url | https://ujmr.umyu.edu.ng/index.php/ujmr/article/view/633 |
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