Protocol for a nested case-control study: identifying neuroimaging biomarkers for the progression of subclinical depression and qi-stagnation constitution to major depressive disorder in adolescents

Protocol for a nested case-control study: identifying neuroimaging biomarkers for the progression of subclinical depression and qi-stagnation constitution to major depressive disorder in adolescents

BackgroundMajor depressive disorder (MDD) frequently results in suboptimal treatment outcomes and elevated recurrence rate, with patients frequently engaging in self-harm and suicidal behavior, thereby placing a heavy burden on families and society. Specifically, MDD in adolescents is linked to an e...

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Bibliographic Details
Main Authors: Jing Wang, Chengfeng Zhang, Yueqi Zhang, Yuanyuan Liu, Jingli Zhang, Xingwei Fang, Wangyang Xia, Yanzhao Xie, Zhongli Lan, Jinhui Wang, Min Lu, Jun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Psychiatry
Subjects:
major depressive disorder
subclinical depression
qi-stagnation constitution
functional magnetic resonance imaging
neuroimaging biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1516846/full
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