Antivirals and monoclonal antibody combination therapy in haematological patients in the omicron era
Abstract: Im We describe here a single-center case series of 27 IC COVID-19 inpatients (mostly with haematological disorders) treated with a combined therapy based on tixagevimab/cilgavimab (T/C) plus small-molecule antivirals (AV), between April 1 2022 and November 30 2022. Keywords: immunocomp...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2024-04-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
| Online Access: | https://www.mjhid.org/mjhid/article/view/5660 |
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| author | Serena Vita Emanuela Giombini Patrizia De Marco Martina Rueca Cesare Ernesto Maria Gruber Alessia Beccacece Laura Scorzolini Valentina Mazzotta Carmen Pinnetti Priscilla Caputi Daniele Focosi Enrico Girardi Andrea Antinori Fabrizio Maggi Alessandra D'Abramo Emanuele Nicastri Investigation Team Spallanzani COVID-19 case |
| author_facet | Serena Vita Emanuela Giombini Patrizia De Marco Martina Rueca Cesare Ernesto Maria Gruber Alessia Beccacece Laura Scorzolini Valentina Mazzotta Carmen Pinnetti Priscilla Caputi Daniele Focosi Enrico Girardi Andrea Antinori Fabrizio Maggi Alessandra D'Abramo Emanuele Nicastri Investigation Team Spallanzani COVID-19 case |
| author_sort | Serena Vita |
| collection | DOAJ |
| description |
Abstract: Im We describe here a single-center case series of 27 IC COVID-19 inpatients (mostly with haematological disorders) treated with a combined therapy based on tixagevimab/cilgavimab (T/C) plus small-molecule antivirals (AV), between April 1 2022 and November 30 2022.
Keywords: immunocompromised; SARS-CoV-2 infection; monoclonal antibodies; antivirals; persistent infection; viral evolution
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| format | Article |
| id | doaj-art-30738854fff242a78d2283cc996ef5ee |
| institution | Kabale University |
| issn | 2035-3006 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-30738854fff242a78d2283cc996ef5ee2025-01-03T00:42:39ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062024-04-0116110.4084/MJHID.2024.043Antivirals and monoclonal antibody combination therapy in haematological patients in the omicron eraSerena Vita0Emanuela Giombini1Patrizia De Marco2Martina Rueca3Cesare Ernesto Maria Gruber4Alessia Beccacece5Laura Scorzolini6Valentina MazzottaCarmen Pinnetti7Priscilla Caputi8Daniele Focosi9Enrico Girardi10Andrea Antinori11Fabrizio Maggi12Alessandra D'Abramo13Emanuele Nicastri14Investigation Team Spallanzani COVID-19 case15National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome ItalyNational Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome ItalyNational Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome ItalyNational Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome ItalyNational Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome ItalyNational Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome ItalyNational Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome ItalyNational Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome ItalyNational Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome ItalyNorth-Western Tuscany Blood Bank, Pisa University Hospital, Pisa, Italy2National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome ItalyNational Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome ItalyNational Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome ItalyOspedale SpallanzaniNational Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome ItalyNational Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS- Rome Italy Abstract: Im We describe here a single-center case series of 27 IC COVID-19 inpatients (mostly with haematological disorders) treated with a combined therapy based on tixagevimab/cilgavimab (T/C) plus small-molecule antivirals (AV), between April 1 2022 and November 30 2022. Keywords: immunocompromised; SARS-CoV-2 infection; monoclonal antibodies; antivirals; persistent infection; viral evolution https://www.mjhid.org/mjhid/article/view/5660 |
| spellingShingle | Serena Vita Emanuela Giombini Patrizia De Marco Martina Rueca Cesare Ernesto Maria Gruber Alessia Beccacece Laura Scorzolini Valentina Mazzotta Carmen Pinnetti Priscilla Caputi Daniele Focosi Enrico Girardi Andrea Antinori Fabrizio Maggi Alessandra D'Abramo Emanuele Nicastri Investigation Team Spallanzani COVID-19 case Antivirals and monoclonal antibody combination therapy in haematological patients in the omicron era Mediterranean Journal of Hematology and Infectious Diseases |
| title | Antivirals and monoclonal antibody combination therapy in haematological patients in the omicron era |
| title_full | Antivirals and monoclonal antibody combination therapy in haematological patients in the omicron era |
| title_fullStr | Antivirals and monoclonal antibody combination therapy in haematological patients in the omicron era |
| title_full_unstemmed | Antivirals and monoclonal antibody combination therapy in haematological patients in the omicron era |
| title_short | Antivirals and monoclonal antibody combination therapy in haematological patients in the omicron era |
| title_sort | antivirals and monoclonal antibody combination therapy in haematological patients in the omicron era |
| url | https://www.mjhid.org/mjhid/article/view/5660 |
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