Granger causality connectivity analysis of persistent atrial fibrillation dynamics reveals posterior wall mechanistic insights

Granger causality connectivity analysis of persistent atrial fibrillation dynamics reveals posterior wall mechanistic insights

Background: Adjunctive posterior wall isolation (PWI) to pulmonary vein isolation (PVI) has not demonstrated convincing benefit during atrial fibrillation (AF) ablation. To provide mechanistic insight for null PWI trials, we undertook Granger causality (GC) analysis of noncontact left atrial (LA) el...

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Main Authors: Joseph Barker, MRes, Arunashis Sau, PhD, Nikesh Bajaj, PhD, Alex Jenkins, MPhys, Alex Sharp, MRCP, Xili Shi, PhD, Xinyang Li, PhD, Nabeela Karim, PhD, Balvinder Handa, PhD, Richard Chambers, MSc, Timothy Betts, PhD, Nicholas S. Peters, MD, FHRS, Tom Wong, MD, Fu Siong Ng, PhD, FHRS
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Heart Rhythm O2
Subjects:
Atrial fibrillation
Granger causality
Posterior wall isolation
Pulmonary vein isolation
Mechanism
Online Access:http://www.sciencedirect.com/science/article/pii/S2666501825001527
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