Drug Screening of Flavonoids as Potential VEGF Inhibitors Through Computational Docking and Cell Models

Drug Screening of Flavonoids as Potential VEGF Inhibitors Through Computational Docking and Cell Models

Vascular endothelial growth factor (VEGF), also known as VEGF-A, has been linked to various diseases, such as wet age-related macular degeneration (wAMD) and cancer. Even though there are VEGF inhibitors that are currently commercially available in clinical applications, severe adverse effects have...

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Bibliographic Details
Main Authors: Shengying Lin, Roy Wai-Lun Tang, Yutong Ye, Chenxi Xia, Jiahui Wu, Ran Duan, Ka-Wing Leung, Tina Ting-Xia Dong, Karl Wah-Keung Tsim
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Molecules
Subjects:
computational docking
drug screening
flavonoids
VEGF inhibitor
angiogenesis
Online Access:https://www.mdpi.com/1420-3049/30/2/257
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