Structural insights into the interplay between microtubule polymerases, γ-tubulin complexes and their receptors

Structural insights into the interplay between microtubule polymerases, γ-tubulin complexes and their receptors

Abstract The γ-tubulin ring complex (γ-TuRC) is a structural template for controlled nucleation of microtubules from α/β-tubulin heterodimers. At the cytoplasmic side of the yeast spindle pole body, the CM1-containing receptor protein Spc72 promotes γ-TuRC assembly from seven γ-tubulin small complex...

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Bibliographic Details
Main Authors: Anjun Zheng, Bram J. A. Vermeulen, Martin Würtz, Annett Neuner, Nicole Lübbehusen, Matthias P. Mayer, Elmar Schiebel, Stefan Pfeffer
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55778-7
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