Brainstem serotonin amplifies nociceptive transmission in a mouse model of Parkinson’s disease

Brainstem serotonin amplifies nociceptive transmission in a mouse model of Parkinson’s disease

Abstract Parkinson’s disease arises from the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to motor symptoms such as akinesia, rigidity, and tremor at rest. The non-motor component of Parkinson’s disease includes increased neuropathic pain, the prevalence of whi...

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Bibliographic Details
Main Authors: Zoé Grivet, Franck Aby, Aude Verboven, Rabia Bouali-Benazzouz, Benjamin Sueur, François Maingret, Frédéric Naudet, Thibault Dhellemmes, Philippe De Deurwaerdere, Abdelhamid Benazzouz, Pascal Fossat
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-024-00857-1
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