Effectiveness of bovine immunoglobulin g against salmonella infections in mice
<b> Aim:</b> This study was aimed to determination of effectiveness of the bovine Immuneglobuline G (IgG) against Salmonella infections caused by Salmonella Dublin, S. Typhimurium, S. Kentucky or S. Anatum.<p> <b> Materials and Methods:</b> Cattle were immunized with in...
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
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| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=1160 |
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| author | Hasan Hüseyin Hadimli Gökçenur Sanioğlu Gölen Zafer Sayın |
| author_facet | Hasan Hüseyin Hadimli Gökçenur Sanioğlu Gölen Zafer Sayın |
| author_sort | Hasan Hüseyin Hadimli |
| collection | DOAJ |
| description | <b> Aim:</b> This study was aimed to determination of effectiveness
of the bovine Immuneglobuline G (IgG) against Salmonella
infections caused by Salmonella Dublin, S. Typhimurium, S.
Kentucky or S. Anatum.<p>
<b> Materials and Methods:</b> Cattle were immunized with inactive
monovalent, bivalent and combined Salmonella vaccines,
three times at 21 days intervals. Immunized cattle blood
samples were collected at 10 days after last vaccination and
titres of IgG to Salmonella antigens were measured micro Serum
Agglutination Test. A total of 100 mice (total 10 vaccine
groups and each group included 10 mice) were challenged
with Salmonella strains by oral route. After challenge, IgG to
mice were administrated by oral route. Mice were observed
for occurence of morbidity and mortality for 20 days. Also,
feacal samples were analyzed to determination influence of
IgG on spread of Salmonella species by feaces.<p>
<b> Results:</b> The antibodies titres in blood of immunized cattle
were found to be high than before vaccination and controls.
The numbers of morbidity and mortality in groups of vaccine
were determined as 9 in combined vaccine (6 in S. Dublin, 2
in S. Typhimurium and 1 in S. Kentucky), 3 in bivalent vaccine
(in S. Typhimurium), and 2 in monovalent (1 in S. Anatum and
S. Kentucky). The re-isolation number of Salmonella strains
were lower from internal organs and feacal samples of mice
in all groups.<p>
<b> Conclusions:</b> In conclusion, it was observed that IgG of immunized
cattle is can be useful for protection against Salmonella
infections, but limited. |
| format | Article |
| id | doaj-art-2ff013cbb5964d18a9ed2024510297b4 |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-2ff013cbb5964d18a9ed2024510297b42025-01-03T01:36:16ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-195333281881160Effectiveness of bovine immunoglobulin g against salmonella infections in miceHasan Hüseyin Hadimli0Gökçenur Sanioğlu GölenZafer Sayın1Selçuk Üniversitesi, Veteriner Fakültesi, Mikrobiyoloji Anabilim Dalı, Alaaddin Keykubat, Yerleşkesi, Konya, TürkiyeSelçuk Üniversitesi, Veteriner Fakültesi, Mikrobiyoloji Anabilim Dalı, Alaaddin Keykubat, Yerleşkesi, Konya, Türkiye<b> Aim:</b> This study was aimed to determination of effectiveness of the bovine Immuneglobuline G (IgG) against Salmonella infections caused by Salmonella Dublin, S. Typhimurium, S. Kentucky or S. Anatum.<p> <b> Materials and Methods:</b> Cattle were immunized with inactive monovalent, bivalent and combined Salmonella vaccines, three times at 21 days intervals. Immunized cattle blood samples were collected at 10 days after last vaccination and titres of IgG to Salmonella antigens were measured micro Serum Agglutination Test. A total of 100 mice (total 10 vaccine groups and each group included 10 mice) were challenged with Salmonella strains by oral route. After challenge, IgG to mice were administrated by oral route. Mice were observed for occurence of morbidity and mortality for 20 days. Also, feacal samples were analyzed to determination influence of IgG on spread of Salmonella species by feaces.<p> <b> Results:</b> The antibodies titres in blood of immunized cattle were found to be high than before vaccination and controls. The numbers of morbidity and mortality in groups of vaccine were determined as 9 in combined vaccine (6 in S. Dublin, 2 in S. Typhimurium and 1 in S. Kentucky), 3 in bivalent vaccine (in S. Typhimurium), and 2 in monovalent (1 in S. Anatum and S. Kentucky). The re-isolation number of Salmonella strains were lower from internal organs and feacal samples of mice in all groups.<p> <b> Conclusions:</b> In conclusion, it was observed that IgG of immunized cattle is can be useful for protection against Salmonella infections, but limited.http://eurasianjvetsci.org/pdf.php3?id=1160passive immunitysalmonellaiggmice |
| spellingShingle | Hasan Hüseyin Hadimli Gökçenur Sanioğlu Gölen Zafer Sayın Effectiveness of bovine immunoglobulin g against salmonella infections in mice Eurasian Journal of Veterinary Sciences passive immunity salmonella igg mice |
| title | Effectiveness of bovine immunoglobulin g against salmonella infections in mice |
| title_full | Effectiveness of bovine immunoglobulin g against salmonella infections in mice |
| title_fullStr | Effectiveness of bovine immunoglobulin g against salmonella infections in mice |
| title_full_unstemmed | Effectiveness of bovine immunoglobulin g against salmonella infections in mice |
| title_short | Effectiveness of bovine immunoglobulin g against salmonella infections in mice |
| title_sort | effectiveness of bovine immunoglobulin g against salmonella infections in mice |
| topic | passive immunity salmonella igg mice |
| url | http://eurasianjvetsci.org/pdf.php3?id=1160 |
| work_keys_str_mv | AT hasanhuseyinhadimli effectivenessofbovineimmunoglobulingagainstsalmonellainfectionsinmice AT gokcenursanioglugolen effectivenessofbovineimmunoglobulingagainstsalmonellainfectionsinmice AT zafersayın effectivenessofbovineimmunoglobulingagainstsalmonellainfectionsinmice |