CAR-T Cells for the Treatment of Central Nervous System Tumours: Known and Emerging Neurotoxicities

The advent of chimeric antigen receptor (CAR)-T cells has recently changed the prognosis of relapsing/refractory diffuse large B-cell lymphomas, showing response rates as high as 60 to 80%. Common toxicities reported in the pivotal clinical trials include the cytokine release syndrome (CRS) and the...

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Bibliographic Details
Main Authors: Leonardo Palazzo, Valentina Pieri, Giulia Berzero, Massimo Filippi
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Brain Sciences
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Online Access:https://www.mdpi.com/2076-3425/14/12/1220
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