EF-P and its paralog EfpL (YeiP) differentially control translation of proline-containing sequences

EF-P and its paralog EfpL (YeiP) differentially control translation of proline-containing sequences

Abstract Polyproline sequences are deleterious to cells because they stall ribosomes. In bacteria, EF-P plays an important role in overcoming such polyproline sequence-induced ribosome stalling. Additionally, numerous bacteria possess an EF-P paralog called EfpL (also known as YeiP) of unknown funct...

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Main Authors: Alina Sieber, Marina Parr, Julian von Ehr, Karthikeyan Dhamotharan, Pavel Kielkowski, Tess Brewer, Anna Schäpers, Ralph Krafczyk, Fei Qi, Andreas Schlundt, Dmitrij Frishman, Jürgen Lassak
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54556-9
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