Endometriosis-associated primary clear cell adenocarcinoma of the urinary bladder: A case report and literature review

Primary clear cell adenocarcinoma (CCA) of the urinary bladder is a rare and aggressive malignancy. Few reports in the literature describe this presentation, as associated with malignant transformation of endometriosis. This case highlights the complex etiology of this variant of CCA, initially diag...

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Main Authors: Meghana Singh, Michael Raver, Bianca DeAgresta, Alexandra Della Pia, Sonam Saxena, Merieme Klobocista, Nitin Yerram
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Urology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214442024002705
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author Meghana Singh
Michael Raver
Bianca DeAgresta
Alexandra Della Pia
Sonam Saxena
Merieme Klobocista
Nitin Yerram
author_facet Meghana Singh
Michael Raver
Bianca DeAgresta
Alexandra Della Pia
Sonam Saxena
Merieme Klobocista
Nitin Yerram
author_sort Meghana Singh
collection DOAJ
description Primary clear cell adenocarcinoma (CCA) of the urinary bladder is a rare and aggressive malignancy. Few reports in the literature describe this presentation, as associated with malignant transformation of endometriosis. This case highlights the complex etiology of this variant of CCA, initially diagnosed using comprehensive imaging and genetic analysis, and subsequently confirmed through extensive surgical intervention and chemotherapy.
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institution Kabale University
issn 2214-4420
language English
publishDate 2025-01-01
publisher Elsevier
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series Urology Case Reports
spelling doaj-art-2f9ff4e7478a4e7eaa33491d268255322025-01-14T04:12:21ZengElsevierUrology Case Reports2214-44202025-01-0158102916Endometriosis-associated primary clear cell adenocarcinoma of the urinary bladder: A case report and literature reviewMeghana Singh0Michael Raver1Bianca DeAgresta2Alexandra Della Pia3Sonam Saxena4Merieme Klobocista5Nitin Yerram6Hackensack University Medical Center, 30 Prospect Avenue, Hackensack, NJ, 07601, USA; Corresponding author. Hackensack University Medical Center, 30 Prospect Avenue, Hackensack, NJ, 07601, USA.Hackensack University Medical Center, 30 Prospect Avenue, Hackensack, NJ, 07601, USADivision of Urologic Oncology, John Theurer Cancer Center at Hackensack Meridian Health, 92 Second St, Hackensack, NJ, 07601, USADivision of Urologic Oncology, John Theurer Cancer Center at Hackensack Meridian Health, 92 Second St, Hackensack, NJ, 07601, USAHackensack University Medical Center, 30 Prospect Avenue, Hackensack, NJ, 07601, USADivision of Urologic Oncology, John Theurer Cancer Center at Hackensack Meridian Health, 92 Second St, Hackensack, NJ, 07601, USAHackensack University Medical Center, 30 Prospect Avenue, Hackensack, NJ, 07601, USA; Division of Urologic Oncology, John Theurer Cancer Center at Hackensack Meridian Health, 92 Second St, Hackensack, NJ, 07601, USAPrimary clear cell adenocarcinoma (CCA) of the urinary bladder is a rare and aggressive malignancy. Few reports in the literature describe this presentation, as associated with malignant transformation of endometriosis. This case highlights the complex etiology of this variant of CCA, initially diagnosed using comprehensive imaging and genetic analysis, and subsequently confirmed through extensive surgical intervention and chemotherapy.http://www.sciencedirect.com/science/article/pii/S2214442024002705Bladder cancerClear cell adenocarcinomaMalignant transformationEndometriosisRadical cystectomyChemotherapy
spellingShingle Meghana Singh
Michael Raver
Bianca DeAgresta
Alexandra Della Pia
Sonam Saxena
Merieme Klobocista
Nitin Yerram
Endometriosis-associated primary clear cell adenocarcinoma of the urinary bladder: A case report and literature review
Urology Case Reports
Bladder cancer
Clear cell adenocarcinoma
Malignant transformation
Endometriosis
Radical cystectomy
Chemotherapy
title Endometriosis-associated primary clear cell adenocarcinoma of the urinary bladder: A case report and literature review
title_full Endometriosis-associated primary clear cell adenocarcinoma of the urinary bladder: A case report and literature review
title_fullStr Endometriosis-associated primary clear cell adenocarcinoma of the urinary bladder: A case report and literature review
title_full_unstemmed Endometriosis-associated primary clear cell adenocarcinoma of the urinary bladder: A case report and literature review
title_short Endometriosis-associated primary clear cell adenocarcinoma of the urinary bladder: A case report and literature review
title_sort endometriosis associated primary clear cell adenocarcinoma of the urinary bladder a case report and literature review
topic Bladder cancer
Clear cell adenocarcinoma
Malignant transformation
Endometriosis
Radical cystectomy
Chemotherapy
url http://www.sciencedirect.com/science/article/pii/S2214442024002705
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