Formulation, Characterisation, and Biocompatibility Assessment of Rifampicin-Loaded Poly(d,l-lactide-co-glycolide) Composites for Local Treatment of Orthopaedic and Wound Infections

Formulation, Characterisation, and Biocompatibility Assessment of Rifampicin-Loaded Poly(d,l-lactide-co-glycolide) Composites for Local Treatment of Orthopaedic and Wound Infections

<b>Background/Objectives:</b> The escalating challenge of antimicrobial resistance (AMR) necessitates the development of targeted antibiotic delivery platforms, minimising systemic administration. Polymer-based drug delivery emerges as a promising solution, ensuring sustained release and...

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Bibliographic Details
Main Authors: Mitali Singhal, Colin C. Seaton, Alexander Surtees, Maria G. Katsikogianni
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceutics
Subjects:
composites
biodegradable
polymer
antimicrobial
cytocompatibility
rifampicin
Online Access:https://www.mdpi.com/1999-4923/16/11/1467
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