G. lamblia and H. pylori infections among mentally challenged individuals in rehabilitation centers in Alexandria, Egypt

Introduction: Concomitant infections with pathogens are common, particularly when there are shared modes of infection or when one pathogen promotes the other. Residence among closed-type care institutions may pose an additional risk of such infections. Mentally challenged patients in rehabilitation...

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Main Authors: Faika I Hassanein, Amany I Shehata, Rashad Abdul-Ghani
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2017-07-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/8783
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author Faika I Hassanein
Amany I Shehata
Rashad Abdul-Ghani
author_facet Faika I Hassanein
Amany I Shehata
Rashad Abdul-Ghani
author_sort Faika I Hassanein
collection DOAJ
description Introduction: Concomitant infections with pathogens are common, particularly when there are shared modes of infection or when one pathogen promotes the other. Residence among closed-type care institutions may pose an additional risk of such infections. Mentally challenged patients in rehabilitation centers constitute one of the special needs groups exposed to parasitic infections, including giardiasis. Several studies reported concomitant infection with G. lamblia and H. pylori worldwide and in Egypt; however, the co-existence of these two pathogens among mentally challenged individuals remains unexplored. The present study aimed to study the prevalence and association between G. lamblia and H. pylori among mentally challenged patients in rehabilitation centers in Alexandria, Egypt. Methodology: 200 individuals admitted to four mental rehabilitation centers in the period from June 2013 to January 2014, who guardians gave informed consent, were recruited. Stool samples were collected and subjected to trichrome stain for G. lamblia and to antigen detection for H. pylori. Results: The overall prevalence rates of G. lamblia and H. pylori were 8.5% and 24.0%, respectively. Monoinfection rates were 5.5% for G. lamblia and 21.0% for H. pylori, while concomitant infection with both species was detected in only 3.0% of cases. However, individuals who were H. pylori-positive were about two times more likely to be infected with G. lamblia than those who were H. pylori-negative (12.5% vs. 7.2%). Conclusions: Mentally challenged individuals in Alexandria harbouring H. pylori are about two times more likely to be exposed to G. lamblia. Large-scale studies are recommended to confirm this association.
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spelling doaj-art-2f50b6774e0e4d46b37444c5c814b7dd2025-08-20T03:52:39ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802017-07-01110710.3855/jidc.8783G. lamblia and H. pylori infections among mentally challenged individuals in rehabilitation centers in Alexandria, EgyptFaika I Hassanein0Amany I Shehata1Rashad Abdul-Ghani2Faculty of Pharmacy and Drug Manufacturing, Pharos University, Alexandria, EgyptHigh Institute of Public Health, Alexandria University, Alexandria, EgyptFaculty of Medicine and Health Sciences, Sana’a University, Sana’a, Yemen Introduction: Concomitant infections with pathogens are common, particularly when there are shared modes of infection or when one pathogen promotes the other. Residence among closed-type care institutions may pose an additional risk of such infections. Mentally challenged patients in rehabilitation centers constitute one of the special needs groups exposed to parasitic infections, including giardiasis. Several studies reported concomitant infection with G. lamblia and H. pylori worldwide and in Egypt; however, the co-existence of these two pathogens among mentally challenged individuals remains unexplored. The present study aimed to study the prevalence and association between G. lamblia and H. pylori among mentally challenged patients in rehabilitation centers in Alexandria, Egypt. Methodology: 200 individuals admitted to four mental rehabilitation centers in the period from June 2013 to January 2014, who guardians gave informed consent, were recruited. Stool samples were collected and subjected to trichrome stain for G. lamblia and to antigen detection for H. pylori. Results: The overall prevalence rates of G. lamblia and H. pylori were 8.5% and 24.0%, respectively. Monoinfection rates were 5.5% for G. lamblia and 21.0% for H. pylori, while concomitant infection with both species was detected in only 3.0% of cases. However, individuals who were H. pylori-positive were about two times more likely to be infected with G. lamblia than those who were H. pylori-negative (12.5% vs. 7.2%). Conclusions: Mentally challenged individuals in Alexandria harbouring H. pylori are about two times more likely to be exposed to G. lamblia. Large-scale studies are recommended to confirm this association. https://jidc.org/index.php/journal/article/view/8783Giardia lambliaHelicobacter pyloriConcomitant infectionMentally challengedAlexandria
spellingShingle Faika I Hassanein
Amany I Shehata
Rashad Abdul-Ghani
G. lamblia and H. pylori infections among mentally challenged individuals in rehabilitation centers in Alexandria, Egypt
Journal of Infection in Developing Countries
Giardia lamblia
Helicobacter pylori
Concomitant infection
Mentally challenged
Alexandria
title G. lamblia and H. pylori infections among mentally challenged individuals in rehabilitation centers in Alexandria, Egypt
title_full G. lamblia and H. pylori infections among mentally challenged individuals in rehabilitation centers in Alexandria, Egypt
title_fullStr G. lamblia and H. pylori infections among mentally challenged individuals in rehabilitation centers in Alexandria, Egypt
title_full_unstemmed G. lamblia and H. pylori infections among mentally challenged individuals in rehabilitation centers in Alexandria, Egypt
title_short G. lamblia and H. pylori infections among mentally challenged individuals in rehabilitation centers in Alexandria, Egypt
title_sort g lamblia and h pylori infections among mentally challenged individuals in rehabilitation centers in alexandria egypt
topic Giardia lamblia
Helicobacter pylori
Concomitant infection
Mentally challenged
Alexandria
url https://jidc.org/index.php/journal/article/view/8783
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AT rashadabdulghani glambliaandhpyloriinfectionsamongmentallychallengedindividualsinrehabilitationcentersinalexandriaegypt