Inhaled corticosteroid effects both eosinophilic and non-eosinophilic inflammation in asthmatic patients

AIM: To determine induced sputum cell counts and interleukin-8 (IL-8), tumor necrosis factor alpha (TNF-α) and leukotriene B4 (LTB4) levels as markers of neutrophilic inflammation in moderate persistent asthma, and to evaluate the response to inhaled steroid therapy.

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Main Authors: Ilknur Basyigit, Fusun Yildiz, Sevgiye Kacar Ozkara, Hasim Boyaci, Ahmet Ilgazli
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Mediators of Inflammation
Subjects:
Online Access:http://dx.doi.org/10.1080/09629350400003118
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author Ilknur Basyigit
Fusun Yildiz
Sevgiye Kacar Ozkara
Hasim Boyaci
Ahmet Ilgazli
author_facet Ilknur Basyigit
Fusun Yildiz
Sevgiye Kacar Ozkara
Hasim Boyaci
Ahmet Ilgazli
author_sort Ilknur Basyigit
collection DOAJ
description AIM: To determine induced sputum cell counts and interleukin-8 (IL-8), tumor necrosis factor alpha (TNF-α) and leukotriene B4 (LTB4) levels as markers of neutrophilic inflammation in moderate persistent asthma, and to evaluate the response to inhaled steroid therapy.
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institution Kabale University
issn 0962-9351
1466-1861
language English
publishDate 2004-01-01
publisher Wiley
record_format Article
series Mediators of Inflammation
spelling doaj-art-2f33c70216fa4579a80ff80d4bc8cdb12025-08-20T03:55:16ZengWileyMediators of Inflammation0962-93511466-18612004-01-0113428529110.1080/09629350400003118Inhaled corticosteroid effects both eosinophilic and non-eosinophilic inflammation in asthmatic patientsIlknur Basyigit0Fusun Yildiz1Sevgiye Kacar Ozkara2Hasim Boyaci3Ahmet Ilgazli4Chest Disease Department , Faculty of Medicine, Kocaeli University, Kocaeli, TurkeyChest Disease Department , Faculty of Medicine, Kocaeli University, Kocaeli, TurkeyPathology Department, Faculty of Medicine, Kocaeli University, Kocaeli, TurkeyChest Disease Department , Faculty of Medicine, Kocaeli University, Kocaeli, TurkeyChest Disease Department , Faculty of Medicine, Kocaeli University, Kocaeli, TurkeyAIM: To determine induced sputum cell counts and interleukin-8 (IL-8), tumor necrosis factor alpha (TNF-α) and leukotriene B4 (LTB4) levels as markers of neutrophilic inflammation in moderate persistent asthma, and to evaluate the response to inhaled steroid therapy.http://dx.doi.org/10.1080/09629350400003118AsthmaSputum eosinophiliaNeutrophilic inflammationInterleukin-8Tumor necrosis factor alpha.
spellingShingle Ilknur Basyigit
Fusun Yildiz
Sevgiye Kacar Ozkara
Hasim Boyaci
Ahmet Ilgazli
Inhaled corticosteroid effects both eosinophilic and non-eosinophilic inflammation in asthmatic patients
Mediators of Inflammation
Asthma
Sputum eosinophilia
Neutrophilic inflammation
Interleukin-8
Tumor necrosis factor alpha.
title Inhaled corticosteroid effects both eosinophilic and non-eosinophilic inflammation in asthmatic patients
title_full Inhaled corticosteroid effects both eosinophilic and non-eosinophilic inflammation in asthmatic patients
title_fullStr Inhaled corticosteroid effects both eosinophilic and non-eosinophilic inflammation in asthmatic patients
title_full_unstemmed Inhaled corticosteroid effects both eosinophilic and non-eosinophilic inflammation in asthmatic patients
title_short Inhaled corticosteroid effects both eosinophilic and non-eosinophilic inflammation in asthmatic patients
title_sort inhaled corticosteroid effects both eosinophilic and non eosinophilic inflammation in asthmatic patients
topic Asthma
Sputum eosinophilia
Neutrophilic inflammation
Interleukin-8
Tumor necrosis factor alpha.
url http://dx.doi.org/10.1080/09629350400003118
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AT fusunyildiz inhaledcorticosteroideffectsbotheosinophilicandnoneosinophilicinflammationinasthmaticpatients
AT sevgiyekacarozkara inhaledcorticosteroideffectsbotheosinophilicandnoneosinophilicinflammationinasthmaticpatients
AT hasimboyaci inhaledcorticosteroideffectsbotheosinophilicandnoneosinophilicinflammationinasthmaticpatients
AT ahmetilgazli inhaledcorticosteroideffectsbotheosinophilicandnoneosinophilicinflammationinasthmaticpatients