The exploration of high production of tiancimycins in Streptomyces sp. CB03234-S revealed potential influences of universal stress proteins on secondary metabolisms of streptomycetes

Abstract Background Universal stress proteins (USPs) are prevalent in various bacteria to cope with different adverse stresses, while their possible effects on secondary metabolisms of hosts are unclear. Tiancimycins (TNMs) are ten-membered endiynes possessing excellent potential for development of...

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Bibliographic Details
Main Authors: Huiming Liu, Zhiying Fan, Nian Tong, Jing Lin, Yong Huang, Yanwen Duan, Xiangcheng Zhu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Microbial Cell Factories
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Online Access:https://doi.org/10.1186/s12934-024-02613-9
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