Characteristics of Pregnant Women with Diabetes Mellitus and Their Babies in Korea

Purpose Pregnant women with diabetes mellitus (DM) and their babies are affected by complications and congenital abnormalities during pregnancy. This study aimed to examine the risk factors for cardiac anomalies and the characteristics of pregestational DM and GDM in mothers and babies in Korea. Met...

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Main Authors: Danbi Kim, Kyoung Soon Cho, Juyoung Lee
Format: Article
Language:English
Published: Korean Society of Neonatology 2024-11-01
Series:Neonatal Medicine
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Online Access:http://www.neo-med.org/upload/pdf/nm-2024-31-3-47.pdf
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author Danbi Kim
Kyoung Soon Cho
Juyoung Lee
author_facet Danbi Kim
Kyoung Soon Cho
Juyoung Lee
author_sort Danbi Kim
collection DOAJ
description Purpose Pregnant women with diabetes mellitus (DM) and their babies are affected by complications and congenital abnormalities during pregnancy. This study aimed to examine the risk factors for cardiac anomalies and the characteristics of pregestational DM and GDM in mothers and babies in Korea. Methods This retrospective study used medical records from Bucheon St. Mary's Hospital between January 2013 and July 2021. We studied 1983 infants, with 335 neonates from mothers with DM. Results Body weight and body mass index were high in mothers with pregestational DM at delivery (p<0.005). The rate of preterm births was lower in the pregestational DM group than in the GDM group. Furthermore, the cardiac anomaly rate was high in the pregestational DM group (p<0.001). The rate of hyperbilirubinemia in the DM group was higher than that in the control group (p<0.001). Multivariate logistic regression analysis revealed no significant risk factors for congenital heart disease. Conclusion DM in pregnant women is associated with congenital anomalies. Therefore, the appropriate management of mothers with DM is important for the prognosis of their neonates.
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spelling doaj-art-2edc4149ce0a42cb8cbd6eaad5e4516a2024-12-10T05:57:30ZengKorean Society of NeonatologyNeonatal Medicine2287-94122287-98032024-11-01313475510.5385/nm.2024.31.3.471099Characteristics of Pregnant Women with Diabetes Mellitus and Their Babies in KoreaDanbi Kim0Kyoung Soon Cho1Juyoung Lee2 Department of Pediatrics, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea Department of Pediatrics, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea Department of Pediatrics, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, KoreaPurpose Pregnant women with diabetes mellitus (DM) and their babies are affected by complications and congenital abnormalities during pregnancy. This study aimed to examine the risk factors for cardiac anomalies and the characteristics of pregestational DM and GDM in mothers and babies in Korea. Methods This retrospective study used medical records from Bucheon St. Mary's Hospital between January 2013 and July 2021. We studied 1983 infants, with 335 neonates from mothers with DM. Results Body weight and body mass index were high in mothers with pregestational DM at delivery (p<0.005). The rate of preterm births was lower in the pregestational DM group than in the GDM group. Furthermore, the cardiac anomaly rate was high in the pregestational DM group (p<0.001). The rate of hyperbilirubinemia in the DM group was higher than that in the control group (p<0.001). Multivariate logistic regression analysis revealed no significant risk factors for congenital heart disease. Conclusion DM in pregnant women is associated with congenital anomalies. Therefore, the appropriate management of mothers with DM is important for the prognosis of their neonates.http://www.neo-med.org/upload/pdf/nm-2024-31-3-47.pdfdiabetes mellitusgestationalcongenital abnormalitiesrisk factors
spellingShingle Danbi Kim
Kyoung Soon Cho
Juyoung Lee
Characteristics of Pregnant Women with Diabetes Mellitus and Their Babies in Korea
Neonatal Medicine
diabetes mellitus
gestational
congenital abnormalities
risk factors
title Characteristics of Pregnant Women with Diabetes Mellitus and Their Babies in Korea
title_full Characteristics of Pregnant Women with Diabetes Mellitus and Their Babies in Korea
title_fullStr Characteristics of Pregnant Women with Diabetes Mellitus and Their Babies in Korea
title_full_unstemmed Characteristics of Pregnant Women with Diabetes Mellitus and Their Babies in Korea
title_short Characteristics of Pregnant Women with Diabetes Mellitus and Their Babies in Korea
title_sort characteristics of pregnant women with diabetes mellitus and their babies in korea
topic diabetes mellitus
gestational
congenital abnormalities
risk factors
url http://www.neo-med.org/upload/pdf/nm-2024-31-3-47.pdf
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AT kyoungsooncho characteristicsofpregnantwomenwithdiabetesmellitusandtheirbabiesinkorea
AT juyounglee characteristicsofpregnantwomenwithdiabetesmellitusandtheirbabiesinkorea