Chemical profiling and bioactivity studies on aerial parts Ammoides atlantica (Coss. et Durieu) H. Wolff
The Algerian endemic plant Ammoides atlantica (Coss. et Durieu) H. Wolff was studied for the chemical profiling and biological activities of its essential oil (EO) and ethanolic extract (EE). The chemical analysis by GC/MS and HPLC/DAD/UV revealed, respectively, the major compounds thymol (39.46%),...
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International Journal of Secondary Metabolite
2024-11-01
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| Series: | International Journal of Secondary Metabolite |
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| Online Access: | https://dergipark.org.tr/en/download/article-file/3776666 |
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| author | Mohamed Hazzit Salah Bendjabeur |
| author_facet | Mohamed Hazzit Salah Bendjabeur |
| author_sort | Mohamed Hazzit |
| collection | DOAJ |
| description | The Algerian endemic plant Ammoides atlantica (Coss. et Durieu) H. Wolff was studied for the chemical profiling and biological activities of its essential oil (EO) and ethanolic extract (EE). The chemical analysis by GC/MS and HPLC/DAD/UV revealed, respectively, the major compounds thymol (39.46%), γ-terpinene (31.74%), and p-cymene (19.01%) in the EO, and apigenin (33.58%), luteolin 7-O-glucoside (20.09%), and luteolin (14.39%) in the EE. The EO exhibited strong antioxidant activity, with a significant ABTS•+ scavenging capacity (IC50 = 2.79 µg/mL) compared to EE, Trolox, and BHT. The EE showed comparable effects to BHT in DPPH scavenging and reducing power tests. Moreover, the EO demonstrated noteworthy antibacterial activity against S. aureus, E. coli, and P. aeruginosa, with inhibition zone diameters ranging from 32.1 to 70 mm and MICs below 0.3 to 5 mg/mL. Furthermore, the EE exhibited strong anti-inflammatory activity by inhibiting hemolysis of red blood cells >70% at a concentration of 20 µg/mL. |
| format | Article |
| id | doaj-art-2eb9d428388244d8a5aa749ade0f0435 |
| institution | Kabale University |
| issn | 2148-6905 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | International Journal of Secondary Metabolite |
| record_format | Article |
| series | International Journal of Secondary Metabolite |
| spelling | doaj-art-2eb9d428388244d8a5aa749ade0f04352024-12-06T09:58:39ZengInternational Journal of Secondary MetaboliteInternational Journal of Secondary Metabolite2148-69052024-11-0111468769910.21448/ijsm.1448014618Chemical profiling and bioactivity studies on aerial parts Ammoides atlantica (Coss. et Durieu) H. WolffMohamed Hazzit0https://orcid.org/0000-0001-8848-502XSalah Bendjabeur1https://orcid.org/0009-0006-6997-9546National High School of AgronomyUniversity of Algiers 1The Algerian endemic plant Ammoides atlantica (Coss. et Durieu) H. Wolff was studied for the chemical profiling and biological activities of its essential oil (EO) and ethanolic extract (EE). The chemical analysis by GC/MS and HPLC/DAD/UV revealed, respectively, the major compounds thymol (39.46%), γ-terpinene (31.74%), and p-cymene (19.01%) in the EO, and apigenin (33.58%), luteolin 7-O-glucoside (20.09%), and luteolin (14.39%) in the EE. The EO exhibited strong antioxidant activity, with a significant ABTS•+ scavenging capacity (IC50 = 2.79 µg/mL) compared to EE, Trolox, and BHT. The EE showed comparable effects to BHT in DPPH scavenging and reducing power tests. Moreover, the EO demonstrated noteworthy antibacterial activity against S. aureus, E. coli, and P. aeruginosa, with inhibition zone diameters ranging from 32.1 to 70 mm and MICs below 0.3 to 5 mg/mL. Furthermore, the EE exhibited strong anti-inflammatory activity by inhibiting hemolysis of red blood cells >70% at a concentration of 20 µg/mL.https://dergipark.org.tr/en/download/article-file/3776666ammoides atlanticaessential oilethanolic extractchemical profilingbioactivityammoides atlanticaessential oilethanolic extractchemical profilingbioactivity |
| spellingShingle | Mohamed Hazzit Salah Bendjabeur Chemical profiling and bioactivity studies on aerial parts Ammoides atlantica (Coss. et Durieu) H. Wolff International Journal of Secondary Metabolite ammoides atlantica essential oil ethanolic extract chemical profiling bioactivity ammoides atlantica essential oil ethanolic extract chemical profiling bioactivity |
| title | Chemical profiling and bioactivity studies on aerial parts Ammoides atlantica (Coss. et Durieu) H. Wolff |
| title_full | Chemical profiling and bioactivity studies on aerial parts Ammoides atlantica (Coss. et Durieu) H. Wolff |
| title_fullStr | Chemical profiling and bioactivity studies on aerial parts Ammoides atlantica (Coss. et Durieu) H. Wolff |
| title_full_unstemmed | Chemical profiling and bioactivity studies on aerial parts Ammoides atlantica (Coss. et Durieu) H. Wolff |
| title_short | Chemical profiling and bioactivity studies on aerial parts Ammoides atlantica (Coss. et Durieu) H. Wolff |
| title_sort | chemical profiling and bioactivity studies on aerial parts ammoides atlantica coss et durieu h wolff |
| topic | ammoides atlantica essential oil ethanolic extract chemical profiling bioactivity ammoides atlantica essential oil ethanolic extract chemical profiling bioactivity |
| url | https://dergipark.org.tr/en/download/article-file/3776666 |
| work_keys_str_mv | AT mohamedhazzit chemicalprofilingandbioactivitystudiesonaerialpartsammoidesatlanticacossetdurieuhwolff AT salahbendjabeur chemicalprofilingandbioactivitystudiesonaerialpartsammoidesatlanticacossetdurieuhwolff |