Comparative effects of standardized Centella asiatica extract (ECa 233) and its active compound mixture on proteomics and mitochondrial function

Comparative effects of standardized Centella asiatica extract (ECa 233) and its active compound mixture on proteomics and mitochondrial function

Abstract ECa 233 is a standardized extract of Centella asiatica that contains the major active compounds madecassoside (MDS) and asiaticoside (ASS), which can strengthen hippocampal synapses, resulting in a memory-enhancing effect. This study explored the possible mechanisms of ECa 233 related to sy...

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Bibliographic Details
Main Authors: Yingrak Boondam, Narawut Pakaprot, Meng Chieh Yang, Nichawadee Sandech, Arnatchai Maiuthed, Jutima Samer, Kanjanawadee Prasittisa, Jutamas Ruanpang, Chit Care, Srirat Chuayboon
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Triterpenoid glycosides
Madecassoside
Asiaticoside
Mitochondria
SH-SY5Y
Proteomic
Online Access:https://doi.org/10.1038/s41598-025-12622-2
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