Assessment of Hyposalivation and Oral Health-Related Quality of Life in Patients on Polypharmacy – A Cross-Sectional Study

Background: This study is centered on finding the changes in the lifestyle of individuals under polypharmacy by using specific questions about the effects of hyposalivation and collection of saliva. Aim: To evaluate the severity of hyposalivation and oral health-related quality of life in patients o...

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Main Authors: J Juliet Philo D Almeida, Elangovan Somasundaram, Suman J. Lakshmi, Senthilkumar Balasubramaniam
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Indian Academy of Oral Medicine and Radiology
Subjects:
Online Access:https://journals.lww.com/10.4103/jiaomr.jiaomr_106_23
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author J Juliet Philo D Almeida
Elangovan Somasundaram
Suman J. Lakshmi
Senthilkumar Balasubramaniam
author_facet J Juliet Philo D Almeida
Elangovan Somasundaram
Suman J. Lakshmi
Senthilkumar Balasubramaniam
author_sort J Juliet Philo D Almeida
collection DOAJ
description Background: This study is centered on finding the changes in the lifestyle of individuals under polypharmacy by using specific questions about the effects of hyposalivation and collection of saliva. Aim: To evaluate the severity of hyposalivation and oral health-related quality of life in patients on polypharmacy. Objectives: To assess the effects of polypharmacy-induced hyposalivation and oral health-related quality of life according to age and gender. Materials and Methods: Stimulated salivary samples were collected in patients between the ages of 40 and 65 years, both male and female who were taking ≥2 medications daily, using the spit method. The flow was calculated based on the mL/min collecting time. Oral health-related quality of life was assessed using the “Oral Health Impact Profile-14” questionnaire. Statistical Analysis: Mean ± standard deviation (SD) of effects of polypharmacy on salivary flow rate and oral health-related quality of life according to age and gender were described, and multiple group comparisons were conducted using the ANOVA and t-test. Results: The difference between salivary flow rate and age (P = 0.564), gender (P = 0.702), duration of medication (P = 0.06), and number of drugs (P = 0.476) were statistically insignificant. Conclusion: A significance was noted according to gender based on the OHIP-14 questionnaire. There was a strong significance according to gender for the questions in the subdomain “physical disability.”
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issn 0972-1363
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spelling doaj-art-2e8219b9231e401b8227d1b54706cb172025-01-06T15:40:04ZengWolters Kluwer Medknow PublicationsJournal of Indian Academy of Oral Medicine and Radiology0972-13630975-15722024-12-0136440741110.4103/jiaomr.jiaomr_106_23Assessment of Hyposalivation and Oral Health-Related Quality of Life in Patients on Polypharmacy – A Cross-Sectional StudyJ Juliet Philo D AlmeidaElangovan SomasundaramSuman J. LakshmiSenthilkumar BalasubramaniamBackground: This study is centered on finding the changes in the lifestyle of individuals under polypharmacy by using specific questions about the effects of hyposalivation and collection of saliva. Aim: To evaluate the severity of hyposalivation and oral health-related quality of life in patients on polypharmacy. Objectives: To assess the effects of polypharmacy-induced hyposalivation and oral health-related quality of life according to age and gender. Materials and Methods: Stimulated salivary samples were collected in patients between the ages of 40 and 65 years, both male and female who were taking ≥2 medications daily, using the spit method. The flow was calculated based on the mL/min collecting time. Oral health-related quality of life was assessed using the “Oral Health Impact Profile-14” questionnaire. Statistical Analysis: Mean ± standard deviation (SD) of effects of polypharmacy on salivary flow rate and oral health-related quality of life according to age and gender were described, and multiple group comparisons were conducted using the ANOVA and t-test. Results: The difference between salivary flow rate and age (P = 0.564), gender (P = 0.702), duration of medication (P = 0.06), and number of drugs (P = 0.476) were statistically insignificant. Conclusion: A significance was noted according to gender based on the OHIP-14 questionnaire. There was a strong significance according to gender for the questions in the subdomain “physical disability.”https://journals.lww.com/10.4103/jiaomr.jiaomr_106_23hyposalivationohip-14polypharmacy
spellingShingle J Juliet Philo D Almeida
Elangovan Somasundaram
Suman J. Lakshmi
Senthilkumar Balasubramaniam
Assessment of Hyposalivation and Oral Health-Related Quality of Life in Patients on Polypharmacy – A Cross-Sectional Study
Journal of Indian Academy of Oral Medicine and Radiology
hyposalivation
ohip-14
polypharmacy
title Assessment of Hyposalivation and Oral Health-Related Quality of Life in Patients on Polypharmacy – A Cross-Sectional Study
title_full Assessment of Hyposalivation and Oral Health-Related Quality of Life in Patients on Polypharmacy – A Cross-Sectional Study
title_fullStr Assessment of Hyposalivation and Oral Health-Related Quality of Life in Patients on Polypharmacy – A Cross-Sectional Study
title_full_unstemmed Assessment of Hyposalivation and Oral Health-Related Quality of Life in Patients on Polypharmacy – A Cross-Sectional Study
title_short Assessment of Hyposalivation and Oral Health-Related Quality of Life in Patients on Polypharmacy – A Cross-Sectional Study
title_sort assessment of hyposalivation and oral health related quality of life in patients on polypharmacy a cross sectional study
topic hyposalivation
ohip-14
polypharmacy
url https://journals.lww.com/10.4103/jiaomr.jiaomr_106_23
work_keys_str_mv AT jjulietphilodalmeida assessmentofhyposalivationandoralhealthrelatedqualityoflifeinpatientsonpolypharmacyacrosssectionalstudy
AT elangovansomasundaram assessmentofhyposalivationandoralhealthrelatedqualityoflifeinpatientsonpolypharmacyacrosssectionalstudy
AT sumanjlakshmi assessmentofhyposalivationandoralhealthrelatedqualityoflifeinpatientsonpolypharmacyacrosssectionalstudy
AT senthilkumarbalasubramaniam assessmentofhyposalivationandoralhealthrelatedqualityoflifeinpatientsonpolypharmacyacrosssectionalstudy