Gasdermin D regulates the activation of EGFR in colorectal cancer
Abstract Background Gasdermin D (GSDMD) is a key effector molecule that activates pyroptosis through its N terminal domain (GSDMD-NT). However, the roles of GSDMD in colorectal cancer (CRC) have not been fully explored. The role of the full-length GSDMD (GSDMD-FL) is also not clear. In this study, w...
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Main Authors: | Ying Li, Jiayao Chen, Huijun Liang, Qindan Du, Jingjie Shen, Xiaoying Wang |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-12-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-024-05984-0 |
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