Caffeine intake is nonlinearly associated with muscle mass in young and middle-aged US adults
Abstract Background Recent studies have indicated that coffee consumption is inversely correlated with sarcopenia in the elderly population. Data regarding the association between caffeine intake and muscle mass in young adults are scarce. Objective We aimed to investigate how dietary caffeine corre...
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| Format: | Article |
| Language: | English |
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BMC
2024-11-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-024-08063-z |
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| author | Lingling Zhou Huanjia Qu Jing Wang Lan Shou Qiuling Zhang Cui Zhang |
| author_facet | Lingling Zhou Huanjia Qu Jing Wang Lan Shou Qiuling Zhang Cui Zhang |
| author_sort | Lingling Zhou |
| collection | DOAJ |
| description | Abstract Background Recent studies have indicated that coffee consumption is inversely correlated with sarcopenia in the elderly population. Data regarding the association between caffeine intake and muscle mass in young adults are scarce. Objective We aimed to investigate how dietary caffeine correlates with muscle mass and sarcopenia in the young and middle-aged people. Methods We performed a cross-sectional study utilizing data from NHANES. Muscle mass was evaluated using DXA and caffeine intake was derived from 24-h dietary recalls. Multivariable regression analysis was adopted to explore association between caffeine and sarcopenia. Restricted cubic spline analysis was conducted to investigate dose-response effect of dietary caffeine on muscle mass. Mediation effect of high-sensitivity C reactive protein was examined by mediation analysis. Results A total of 9116 adults aged from 20 to 59 years old were included. Higher ingestion of caffeine was not associated with sarcopenia. Association between dietary caffeine and muscle mass was found to be W-shaped in males and U-shaped in young females, wherein mediation effect of hs-CRP was not discovered. Conclusions Caffeine consumption is associated with muscle mass in a nonlinear pattern. ASMI peaks at a daily caffeine intake of 1.23 mg/kg in young adults, while 0.64–1.49 mg/kg is recommended for middle-aged men. |
| format | Article |
| id | doaj-art-2e23f5d5f70f48aebffccf134feccc2f |
| institution | Kabale University |
| issn | 1471-2474 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj-art-2e23f5d5f70f48aebffccf134feccc2f2024-11-24T12:03:39ZengBMCBMC Musculoskeletal Disorders1471-24742024-11-0125111010.1186/s12891-024-08063-zCaffeine intake is nonlinearly associated with muscle mass in young and middle-aged US adultsLingling Zhou0Huanjia Qu1Jing Wang2Lan Shou3Qiuling Zhang4Cui Zhang5Metabolic Disease Center, Department of Endocrinology and Metabolism, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal UniversityMetabolic Disease Center, Department of Endocrinology and Metabolism, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal UniversityMetabolic Disease Center, Department of Endocrinology and Metabolism, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal UniversityMetabolic Disease Center, Department of Endocrinology and Metabolism, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal UniversityMetabolic Disease Center, Department of Endocrinology and Metabolism, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal UniversityDepartment of Gastroenterology, Shanghai Tenth People’s hospital of Tongji UniversityAbstract Background Recent studies have indicated that coffee consumption is inversely correlated with sarcopenia in the elderly population. Data regarding the association between caffeine intake and muscle mass in young adults are scarce. Objective We aimed to investigate how dietary caffeine correlates with muscle mass and sarcopenia in the young and middle-aged people. Methods We performed a cross-sectional study utilizing data from NHANES. Muscle mass was evaluated using DXA and caffeine intake was derived from 24-h dietary recalls. Multivariable regression analysis was adopted to explore association between caffeine and sarcopenia. Restricted cubic spline analysis was conducted to investigate dose-response effect of dietary caffeine on muscle mass. Mediation effect of high-sensitivity C reactive protein was examined by mediation analysis. Results A total of 9116 adults aged from 20 to 59 years old were included. Higher ingestion of caffeine was not associated with sarcopenia. Association between dietary caffeine and muscle mass was found to be W-shaped in males and U-shaped in young females, wherein mediation effect of hs-CRP was not discovered. Conclusions Caffeine consumption is associated with muscle mass in a nonlinear pattern. ASMI peaks at a daily caffeine intake of 1.23 mg/kg in young adults, while 0.64–1.49 mg/kg is recommended for middle-aged men.https://doi.org/10.1186/s12891-024-08063-zCaffeineMuscle massSarcopeniaNHANES |
| spellingShingle | Lingling Zhou Huanjia Qu Jing Wang Lan Shou Qiuling Zhang Cui Zhang Caffeine intake is nonlinearly associated with muscle mass in young and middle-aged US adults BMC Musculoskeletal Disorders Caffeine Muscle mass Sarcopenia NHANES |
| title | Caffeine intake is nonlinearly associated with muscle mass in young and middle-aged US adults |
| title_full | Caffeine intake is nonlinearly associated with muscle mass in young and middle-aged US adults |
| title_fullStr | Caffeine intake is nonlinearly associated with muscle mass in young and middle-aged US adults |
| title_full_unstemmed | Caffeine intake is nonlinearly associated with muscle mass in young and middle-aged US adults |
| title_short | Caffeine intake is nonlinearly associated with muscle mass in young and middle-aged US adults |
| title_sort | caffeine intake is nonlinearly associated with muscle mass in young and middle aged us adults |
| topic | Caffeine Muscle mass Sarcopenia NHANES |
| url | https://doi.org/10.1186/s12891-024-08063-z |
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