Adrenal adenoma secreting 17-hydroxyprogesterone mimicking non-classical 21-hydroxylase deficiency

Adrenal adenoma secreting 17-hydroxyprogesterone mimicking non-classical 21-hydroxylase deficiency

In adrenal steroidogenesis, 17-hydroxyprogesterone (17-OHP) is a substrate for 21-hydroxylase, one of the crucial enzymes of the cortisol and aldosterone biosynthesis pathway. Thus, measurement serum 17-OHP concentration is used when the diagnosis of congenital adrenal hyperplasia (CAH) due to 21-hy...

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Bibliographic Details
Main Authors: Beata Woźniak, Dorota Leszczyńska, Alicja Szatko, Karolina Nowak, Radosław Samsel, Anna Siejka, Lucyna Papierska, Wojciech Zgliczyński, Henrik Falhammar, Piotr Glinicki
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Endocrinology
Subjects:
congenital adrenal hyperplasia
CAH
adrenal incidentaloma
adrenal tumors
urine steroid profile
17-OHP
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1499836/full
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https://www.frontiersin.org/articles/10.3389/fendo.2024.1499836/full

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