Applications of electrochemical impedance spectroscopy in disease diagnosis—A review
Electrochemical impedance spectroscopy (EIS) is a reliable technique for gathering information about electrochemical process occurring at the electrode surface and investigating properties of materials. Furthermore, EIS technique can be a very versatile and valuable tool in analytical assays for det...
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Elsevier
2024-12-01
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| Series: | Sensors and Actuators Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666053924000213 |
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| author | José A. Ribeiro Pedro A.S. Jorge |
| author_facet | José A. Ribeiro Pedro A.S. Jorge |
| author_sort | José A. Ribeiro |
| collection | DOAJ |
| description | Electrochemical impedance spectroscopy (EIS) is a reliable technique for gathering information about electrochemical process occurring at the electrode surface and investigating properties of materials. Furthermore, EIS technique can be a very versatile and valuable tool in analytical assays for detection and quantification of several chemically and biologically relevant (bio)molecules. The first part of this Review (Introduction) provides brief insights into (i) theoretical aspects of EIS, (ii) the instrumentation required to perform the EIS studies and (iii) the most relevant representations of impedance experimental data (such as Nyquist and Bode plots). In the end of this section, (iv) theoretical aspects regarding the fitting of the Randles circuit to experimental data are addressed, not only to obtain information about electrochemical processes but also to illustrate its utility for analytical purposes. The second part of the Review (Impedimetric Detection of Disease Biomarkers) focuses on the applications of EIS in the biomedical field, particularly as analytical technique in electrochemical sensors and biosensors for screening disease biomarkers. In the last section (Conclusions and Perspectives), we discuss main achievements of EIS technique in analytical assays and provide some perspectives, challenges and future applications in the biomedical field. |
| format | Article |
| id | doaj-art-2dc5a07f1cbf4367a269cdfe8a23f489 |
| institution | Kabale University |
| issn | 2666-0539 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Sensors and Actuators Reports |
| spelling | doaj-art-2dc5a07f1cbf4367a269cdfe8a23f4892024-11-15T06:14:54ZengElsevierSensors and Actuators Reports2666-05392024-12-018100205Applications of electrochemical impedance spectroscopy in disease diagnosis—A reviewJosé A. Ribeiro0Pedro A.S. Jorge1CIQUP/IMS, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre 687, s/n, Porto 4169-007, Portugal; Corresponding author.INESC TEC–Institute for Systems and Computer Engineering, Technology and Science, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal; Department of Physics and Astronomy, Faculty of Sciences, University of Porto, Rua do Campo Alegre 687, s/n, Porto 4169-007, PortugalElectrochemical impedance spectroscopy (EIS) is a reliable technique for gathering information about electrochemical process occurring at the electrode surface and investigating properties of materials. Furthermore, EIS technique can be a very versatile and valuable tool in analytical assays for detection and quantification of several chemically and biologically relevant (bio)molecules. The first part of this Review (Introduction) provides brief insights into (i) theoretical aspects of EIS, (ii) the instrumentation required to perform the EIS studies and (iii) the most relevant representations of impedance experimental data (such as Nyquist and Bode plots). In the end of this section, (iv) theoretical aspects regarding the fitting of the Randles circuit to experimental data are addressed, not only to obtain information about electrochemical processes but also to illustrate its utility for analytical purposes. The second part of the Review (Impedimetric Detection of Disease Biomarkers) focuses on the applications of EIS in the biomedical field, particularly as analytical technique in electrochemical sensors and biosensors for screening disease biomarkers. In the last section (Conclusions and Perspectives), we discuss main achievements of EIS technique in analytical assays and provide some perspectives, challenges and future applications in the biomedical field.http://www.sciencedirect.com/science/article/pii/S2666053924000213EISImpedimetric sensorsDetectionBiomarkers |
| spellingShingle | José A. Ribeiro Pedro A.S. Jorge Applications of electrochemical impedance spectroscopy in disease diagnosis—A review Sensors and Actuators Reports EIS Impedimetric sensors Detection Biomarkers |
| title | Applications of electrochemical impedance spectroscopy in disease diagnosis—A review |
| title_full | Applications of electrochemical impedance spectroscopy in disease diagnosis—A review |
| title_fullStr | Applications of electrochemical impedance spectroscopy in disease diagnosis—A review |
| title_full_unstemmed | Applications of electrochemical impedance spectroscopy in disease diagnosis—A review |
| title_short | Applications of electrochemical impedance spectroscopy in disease diagnosis—A review |
| title_sort | applications of electrochemical impedance spectroscopy in disease diagnosis a review |
| topic | EIS Impedimetric sensors Detection Biomarkers |
| url | http://www.sciencedirect.com/science/article/pii/S2666053924000213 |
| work_keys_str_mv | AT josearibeiro applicationsofelectrochemicalimpedancespectroscopyindiseasediagnosisareview AT pedroasjorge applicationsofelectrochemicalimpedancespectroscopyindiseasediagnosisareview |