Tyrosine phosphatase SHP2 accelerated ovarian cancer via modulating integrin/ E-Cadherin/ ZEB1 induced EMT

Tyrosine phosphatase SHP2 accelerated ovarian cancer via modulating integrin/ E-Cadherin/ ZEB1 induced EMT

Abstract This article focusing on examining the function and further, molecular function of SHP2 in ovarian cancer (OC). For the molecular mechanism, bioinformatics was applied to study the specifically expressed genes in ovarian cancer ; the western blotting was applied to identify the EGF, p-SHP2,...

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Bibliographic Details
Main Authors: Xiaofei Li, Haibo Zhang, Jianan Dong, Juan Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Ovarian cancer
SHP2
Eintegrin/E-Cadherin signalling pathway
Epithelial mesenchymal transition
Online Access:https://doi.org/10.1038/s41598-025-85445-w
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