Adenosine signaling in tumor-associated macrophages and targeting adenosine signaling for cancer therapy

This review examined the critical role of adenosine signaling in modulating the behavior of tumor-associated macrophages (TAMs), a key determinant of the tumor microenvironment (TME). Adenosine is an immunosuppressive metabolite that is highly enriched in the TME due to elevated expression of adenos...

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Bibliographic Details
Main Authors: Lei Yang, Yi Zhang, Li Yang
Format: Article
Language:English
Published: China Anti-Cancer Association 2024-11-01
Series:Cancer Biology & Medicine
Subjects:
Online Access:https://www.cancerbiomed.org/content/21/11/995
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