A bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseases

Electrochemical biosensors can provide an economical, accurate and rapid method for early screening of disease biomarkers in clinical medicine due to their high sensitivity, selectivity, portability, low cost and easy manufacturing, and multiplexing capability. Tear, a fluid naturally secreted by th...

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Main Authors: Fushen Zhang, Weiye Xu, Zejun Deng, Jufang Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1487981/full
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author Fushen Zhang
Weiye Xu
Zejun Deng
Jufang Huang
author_facet Fushen Zhang
Weiye Xu
Zejun Deng
Jufang Huang
author_sort Fushen Zhang
collection DOAJ
description Electrochemical biosensors can provide an economical, accurate and rapid method for early screening of disease biomarkers in clinical medicine due to their high sensitivity, selectivity, portability, low cost and easy manufacturing, and multiplexing capability. Tear, a fluid naturally secreted by the human body, is not only easily accessible but also contains a great deal of biological information. However, no bibliometric studies focus on applying electrochemical sensors in tear/eye diseases. Therefore, we utilized VOSviewer and CiteSpace, to perform a detailed bibliometric analysis of 114 papers in the field of research on the application of tear in electrochemical biosensors screened from Web of Science with the combination of Scimago Graphica and Microsoft Excel for visualization to show the current research hotspots and future trends. The results show that the research in this field started in 2008 and experienced an emerging period in recent years. Researchers from China and the United States mainly contributed to the thriving research areas, with 41 and 29 articles published, respectively. Joseph Wang from the University of California San Diego is the most influential author in the field, and Biosensors & Bioelectronics is the journal with the most published research and the most cited journal. The highest appearance keywords were “biosensor” and “tear glucose,” while the most recent booming keywords “diagnosis” and “in-vivo” were. In conclusion, this study elucidates current trends, hotspots, and emerging frontiers, and provides future biomarkers of ocular and systemic diseases by electrochemical sensors in tear with new ideas and opinions.
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spelling doaj-art-2d9bc3f47984482a9f4e24f3bb4da54f2025-01-10T06:10:38ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-01-011110.3389/fmed.2024.14879811487981A bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseasesFushen Zhang0Weiye Xu1Zejun Deng2Jufang Huang3Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, ChinaDepartment of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, ChinaSchool of Materials Science and Engineering, State Key Laboratory of Powder Metallurgy, Central South University, Changsha, ChinaDepartment of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, ChinaElectrochemical biosensors can provide an economical, accurate and rapid method for early screening of disease biomarkers in clinical medicine due to their high sensitivity, selectivity, portability, low cost and easy manufacturing, and multiplexing capability. Tear, a fluid naturally secreted by the human body, is not only easily accessible but also contains a great deal of biological information. However, no bibliometric studies focus on applying electrochemical sensors in tear/eye diseases. Therefore, we utilized VOSviewer and CiteSpace, to perform a detailed bibliometric analysis of 114 papers in the field of research on the application of tear in electrochemical biosensors screened from Web of Science with the combination of Scimago Graphica and Microsoft Excel for visualization to show the current research hotspots and future trends. The results show that the research in this field started in 2008 and experienced an emerging period in recent years. Researchers from China and the United States mainly contributed to the thriving research areas, with 41 and 29 articles published, respectively. Joseph Wang from the University of California San Diego is the most influential author in the field, and Biosensors & Bioelectronics is the journal with the most published research and the most cited journal. The highest appearance keywords were “biosensor” and “tear glucose,” while the most recent booming keywords “diagnosis” and “in-vivo” were. In conclusion, this study elucidates current trends, hotspots, and emerging frontiers, and provides future biomarkers of ocular and systemic diseases by electrochemical sensors in tear with new ideas and opinions.https://www.frontiersin.org/articles/10.3389/fmed.2024.1487981/fullelectrochemical biosensorseye diseasestearsBibliometricsVOSviewerCiteSpace
spellingShingle Fushen Zhang
Weiye Xu
Zejun Deng
Jufang Huang
A bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseases
Frontiers in Medicine
electrochemical biosensors
eye diseases
tears
Bibliometrics
VOSviewer
CiteSpace
title A bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseases
title_full A bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseases
title_fullStr A bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseases
title_full_unstemmed A bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseases
title_short A bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseases
title_sort bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseases
topic electrochemical biosensors
eye diseases
tears
Bibliometrics
VOSviewer
CiteSpace
url https://www.frontiersin.org/articles/10.3389/fmed.2024.1487981/full
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