The epidermal lipid-microbiome loop and immunity: Important players in atopic dermatitis

The epidermal lipid-microbiome loop and immunity: Important players in atopic dermatitis

Background: The promotion of epidermal barrier dysfunction is attributed to abnormalities in the lipid-microbiome positive feedback loop which significantly influences the imbalance of the epithelial immune microenvironment (EIME) in atopic dermatitis (AD). This imbalance encompasses impaired lamell...

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Bibliographic Details
Main Authors: Junchao Wu, Lisha Li, Tingrui Zhang, Jiaye Lu, Zongguang Tai, Quangang Zhu, Zhongjian Chen
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Advanced Research
Subjects:
Atopic dermatitis
Lipid-microbiome loop
Adaptive immunity
Epidermal lipid
Microbe
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123224000882
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