Revisiting the female germline cell development
The formation of the female germline is the fundamental process in most flowering plants’ sexual reproduction. In Arabidopsis, only one somatic cell obtains the female germline fate, and this process is regulated by different pathways. Megaspore mother cell (MMC) is the first female germline, and un...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Plant Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpls.2024.1525729/full |
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| _version_ | 1841536778858659840 |
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| author | Youmei Huang Yunlong Zhang Jiahong Yang Xinpeng Xi Yanfen Liu Hanyang Cai Yuan Qin |
| author_facet | Youmei Huang Yunlong Zhang Jiahong Yang Xinpeng Xi Yanfen Liu Hanyang Cai Yuan Qin |
| author_sort | Youmei Huang |
| collection | DOAJ |
| description | The formation of the female germline is the fundamental process in most flowering plants’ sexual reproduction. In Arabidopsis, only one somatic cell obtains the female germline fate, and this process is regulated by different pathways. Megaspore mother cell (MMC) is the first female germline, and understanding MMC development is essential for comprehending the complex mechanisms of plant reproduction processes. Recently, more advanced technologies such as whole-mount single-molecule fluorescence in situ hybridization (smFISH), laser-assisted microdissection (LCM), chromatin immunoprecipitation/sequencing, and CRISPR gene editing have provided opportunities to reveal the mechanism of female germline development at different stages. Single-cell transcriptome/spatial transcriptomics analysis helps to investigate complex cellular systems at the single-cell level, reflecting the biological complexity of different cell types. In this review, we highlight recent progress that facilitates the development of the female germline to explore the roles of crucial gene regulatory networks, epigenetic pathways, cell-cycle regulators, and phytohormones in this process. This review discusses three key phases in female germline development and provides the possibility of distinct pathways restricting germline development in the future. |
| format | Article |
| id | doaj-art-2d35104cde274b7eb514733cef79ba3d |
| institution | Kabale University |
| issn | 1664-462X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj-art-2d35104cde274b7eb514733cef79ba3d2025-01-14T10:33:36ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2025-01-011510.3389/fpls.2024.15257291525729Revisiting the female germline cell developmentYoumei HuangYunlong ZhangJiahong YangXinpeng XiYanfen LiuHanyang CaiYuan QinThe formation of the female germline is the fundamental process in most flowering plants’ sexual reproduction. In Arabidopsis, only one somatic cell obtains the female germline fate, and this process is regulated by different pathways. Megaspore mother cell (MMC) is the first female germline, and understanding MMC development is essential for comprehending the complex mechanisms of plant reproduction processes. Recently, more advanced technologies such as whole-mount single-molecule fluorescence in situ hybridization (smFISH), laser-assisted microdissection (LCM), chromatin immunoprecipitation/sequencing, and CRISPR gene editing have provided opportunities to reveal the mechanism of female germline development at different stages. Single-cell transcriptome/spatial transcriptomics analysis helps to investigate complex cellular systems at the single-cell level, reflecting the biological complexity of different cell types. In this review, we highlight recent progress that facilitates the development of the female germline to explore the roles of crucial gene regulatory networks, epigenetic pathways, cell-cycle regulators, and phytohormones in this process. This review discusses three key phases in female germline development and provides the possibility of distinct pathways restricting germline development in the future.https://www.frontiersin.org/articles/10.3389/fpls.2024.1525729/fullMMCplant reproduction processesepigenetic pathwayscell-cycle regulatorsphytohormones |
| spellingShingle | Youmei Huang Yunlong Zhang Jiahong Yang Xinpeng Xi Yanfen Liu Hanyang Cai Yuan Qin Revisiting the female germline cell development Frontiers in Plant Science MMC plant reproduction processes epigenetic pathways cell-cycle regulators phytohormones |
| title | Revisiting the female germline cell development |
| title_full | Revisiting the female germline cell development |
| title_fullStr | Revisiting the female germline cell development |
| title_full_unstemmed | Revisiting the female germline cell development |
| title_short | Revisiting the female germline cell development |
| title_sort | revisiting the female germline cell development |
| topic | MMC plant reproduction processes epigenetic pathways cell-cycle regulators phytohormones |
| url | https://www.frontiersin.org/articles/10.3389/fpls.2024.1525729/full |
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