Research Progress on Immune Regulation Activities of Marine Sulfate Polysaccharides
With changes in modern lifestyles, weakened immunity becomes a health problem for an increasing number of people. The development of natural active products with immunomodulatory activity becomes a popular research topic. Marine sulfated polysaccharides are natural active products that are rich in s...
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| Format: | Article |
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The editorial department of Science and Technology of Food Industry
2025-01-01
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| Series: | Shipin gongye ke-ji |
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| Online Access: | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024020170 |
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| author | Qiuyu CHEN Ran ZHAO Meishan MENG Xinyu DOU Biyi CHEN Qiancheng ZHAO Ying LI |
| author_facet | Qiuyu CHEN Ran ZHAO Meishan MENG Xinyu DOU Biyi CHEN Qiancheng ZHAO Ying LI |
| author_sort | Qiuyu CHEN |
| collection | DOAJ |
| description | With changes in modern lifestyles, weakened immunity becomes a health problem for an increasing number of people. The development of natural active products with immunomodulatory activity becomes a popular research topic. Marine sulfated polysaccharides are natural active products that are rich in sulfate groups and are extracted and isolated from marine organisms. They have a unique structure and multiple biological activities and have shown great potential with regard to having immune regulatory activity. To better understand the effects of marine sulfated polysaccharides on immune regulatory activity and the associated underlying mechanisms, this article was designed to analyse and summarize the current research literature on marine sulfated polysaccharides. The types of marine sulfated polysaccharides are summarized based on their structure and source, with a focus on functions involving regulating macrophages, natural killer cells, T/B lymphocytes, complement systems, and gut microbiota. The immune regulatory activity of marine sulfated polysaccharides and the underlying mechanisms are summarized. This article provides a theoretical basis for subsequent research on the immunomodulatory activity and structure-activity relationships of marine sulfated polysaccharides and provides novel ideas for the development of new marine sulfated polysaccharide immunoenhancers. In the future, functional foods or special medical foods based on marine sulfated polysaccharides designed to treat immune deficiency, tumours, and autoimmune diseases may be developed, and these foods will play a positive role in promoting the development of the food industry and human health. |
| format | Article |
| id | doaj-art-2cfdbf30ac5045d2b61b72c7ed24f0f5 |
| institution | Kabale University |
| issn | 1002-0306 |
| language | zho |
| publishDate | 2025-01-01 |
| publisher | The editorial department of Science and Technology of Food Industry |
| record_format | Article |
| series | Shipin gongye ke-ji |
| spelling | doaj-art-2cfdbf30ac5045d2b61b72c7ed24f0f52025-01-10T06:49:17ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062025-01-0146141342310.13386/j.issn1002-0306.20240201702024020170-1Research Progress on Immune Regulation Activities of Marine Sulfate PolysaccharidesQiuyu CHEN0Ran ZHAO1Meishan MENG2Xinyu DOU3Biyi CHEN4Qiancheng ZHAO5Ying LI6College of Food Science and Engineering, Dalian Ocean University, Dalian 116023, ChinaCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, ChinaCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, ChinaCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, ChinaCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, ChinaCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, ChinaCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, ChinaWith changes in modern lifestyles, weakened immunity becomes a health problem for an increasing number of people. The development of natural active products with immunomodulatory activity becomes a popular research topic. Marine sulfated polysaccharides are natural active products that are rich in sulfate groups and are extracted and isolated from marine organisms. They have a unique structure and multiple biological activities and have shown great potential with regard to having immune regulatory activity. To better understand the effects of marine sulfated polysaccharides on immune regulatory activity and the associated underlying mechanisms, this article was designed to analyse and summarize the current research literature on marine sulfated polysaccharides. The types of marine sulfated polysaccharides are summarized based on their structure and source, with a focus on functions involving regulating macrophages, natural killer cells, T/B lymphocytes, complement systems, and gut microbiota. The immune regulatory activity of marine sulfated polysaccharides and the underlying mechanisms are summarized. This article provides a theoretical basis for subsequent research on the immunomodulatory activity and structure-activity relationships of marine sulfated polysaccharides and provides novel ideas for the development of new marine sulfated polysaccharide immunoenhancers. In the future, functional foods or special medical foods based on marine sulfated polysaccharides designed to treat immune deficiency, tumours, and autoimmune diseases may be developed, and these foods will play a positive role in promoting the development of the food industry and human health.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024020170marine sulfate polysaccharideimmune regulationmechanismgut microbiota |
| spellingShingle | Qiuyu CHEN Ran ZHAO Meishan MENG Xinyu DOU Biyi CHEN Qiancheng ZHAO Ying LI Research Progress on Immune Regulation Activities of Marine Sulfate Polysaccharides Shipin gongye ke-ji marine sulfate polysaccharide immune regulation mechanism gut microbiota |
| title | Research Progress on Immune Regulation Activities of Marine Sulfate Polysaccharides |
| title_full | Research Progress on Immune Regulation Activities of Marine Sulfate Polysaccharides |
| title_fullStr | Research Progress on Immune Regulation Activities of Marine Sulfate Polysaccharides |
| title_full_unstemmed | Research Progress on Immune Regulation Activities of Marine Sulfate Polysaccharides |
| title_short | Research Progress on Immune Regulation Activities of Marine Sulfate Polysaccharides |
| title_sort | research progress on immune regulation activities of marine sulfate polysaccharides |
| topic | marine sulfate polysaccharide immune regulation mechanism gut microbiota |
| url | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024020170 |
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