Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical Modeling

In this work the theory of the optical coherence tomography (OCT) signal after sampling, in dispersive media, with noise, and for a turbid medium is presented. The analytical theory is demonstrated with a one-dimensional numerical OCT model for (single) reflectors, dispersive media, and turbid media...

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Main Author: J. Kalkman
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:International Journal of Optics
Online Access:http://dx.doi.org/10.1155/2017/9586067
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author J. Kalkman
author_facet J. Kalkman
author_sort J. Kalkman
collection DOAJ
description In this work the theory of the optical coherence tomography (OCT) signal after sampling, in dispersive media, with noise, and for a turbid medium is presented. The analytical theory is demonstrated with a one-dimensional numerical OCT model for (single) reflectors, dispersive media, and turbid media. For dispersive media the deterioration of the OCT axial resolution is quantified analytically and numerically. The OCT signal to noise ratio (SNR) is analyzed in the Fourier-domain and simulated with the numerical model. For an SNR based on the OCT intensity the conventional shot noise limited SNR is derived whereas for an SNR based on the OCT amplitude a 6.7 dB higher SNR is demonstrated. The OCT phase stability is derived in the Fourier-domain as 2SNR−1 and is validated using the numerical OCT model. The OCT single scattering model is simulated with the one-dimensional numerical model and applied to the simulation of an OCT image of a two-layered sample.
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spelling doaj-art-2cebcb7f97104482b15b2272c0dd03e12025-08-20T03:55:15ZengWileyInternational Journal of Optics1687-93841687-93922017-01-01201710.1155/2017/95860679586067Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical ModelingJ. Kalkman0Department of Imaging Physics, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, NetherlandsIn this work the theory of the optical coherence tomography (OCT) signal after sampling, in dispersive media, with noise, and for a turbid medium is presented. The analytical theory is demonstrated with a one-dimensional numerical OCT model for (single) reflectors, dispersive media, and turbid media. For dispersive media the deterioration of the OCT axial resolution is quantified analytically and numerically. The OCT signal to noise ratio (SNR) is analyzed in the Fourier-domain and simulated with the numerical model. For an SNR based on the OCT intensity the conventional shot noise limited SNR is derived whereas for an SNR based on the OCT amplitude a 6.7 dB higher SNR is demonstrated. The OCT phase stability is derived in the Fourier-domain as 2SNR−1 and is validated using the numerical OCT model. The OCT single scattering model is simulated with the one-dimensional numerical model and applied to the simulation of an OCT image of a two-layered sample.http://dx.doi.org/10.1155/2017/9586067
spellingShingle J. Kalkman
Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical Modeling
International Journal of Optics
title Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical Modeling
title_full Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical Modeling
title_fullStr Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical Modeling
title_full_unstemmed Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical Modeling
title_short Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical Modeling
title_sort fourier domain optical coherence tomography signal analysis and numerical modeling
url http://dx.doi.org/10.1155/2017/9586067
work_keys_str_mv AT jkalkman fourierdomainopticalcoherencetomographysignalanalysisandnumericalmodeling