Assessing the predictive potential of ADAM8 for disease control in chronic rhinosinusitis with nasal polyps

Assessing the predictive potential of ADAM8 for disease control in chronic rhinosinusitis with nasal polyps

BackgroundA disintegrin and metalloproteinase 8 (ADAM8) has been implicated in eosinophilic inflammation; however, its role in chronic rhinosinusitis with nasal polyps (CRSwNP) remains to be elucidated. This study aimed to investigate the predictive significance of ADAM8 levels in nasal secretions f...

Full description

Saved in:

Bibliographic Details
Main Authors:	Peiqiang Liu, Meng Liu, Yibin Sun, Weiwei Lei, Yu Xu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-11-01
Series:	Frontiers in Allergy
Subjects:	chronic rhinosinusitis with nasal polyp ADAM8 biomarker endotypes disease control status
Online Access:	https://www.frontiersin.org/articles/10.3389/falgy.2024.1488441/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Predicting the effectiveness of omalizumab in patients with refractory chronic rhinosinusitis with nasal polyps comorbid with asthma based on inflammatory biomarkers
by: Yutong Sima, MD, et al.
Published: (2025-01-01)

Identification of multiple isoforms of glucocorticoid receptor in nasal polyps of patients with chronic rhinosinusitis
by: Shan Shao, et al.
Published: (2022-06-01)

Update on the Biological and Clinical Relevance of Mast Cells in Chronic Rhinosinusitis with Nasal Polyps
by: Luca Giovanni Locatello, et al.
Published: (2024-11-01)

The role of CD24hiCD27+ regulatory B cells in human chronic rhinosinusitis with/without nasal polyps
by: Shiyu Tian, et al.
Published: (2024-11-01)

Chronic rhinosinusitis with nasal polyps: Key considerations in the multidisciplinary team approach
by: Oliver Pfaar, et al.
Published: (2025-01-01)

The influence of the sinonasal microbiome on the development and management of rhinosinusitis
by: Miriam Lang, et al.
Published: (2025-01-01)

What is the impact of biological treatment on sleep quality in chronic rhinosinusitis with nasal polyps patients: a retrospective cross-sectional study
by: Danah Althomaly, et al.
Published: (2024-11-01)

Therapeutic Effectiveness of SNOT 22-Based Interdose Interval Adjustment of Dupilumab for Chronic Rhinosinusitis With Nasal Polyps
by: So Yeon Yoon, et al.
Published: (2024-11-01)

Canadian real-world study of access and clinical results using dupilumab for chronic rhinosinusitis with polyps
by: Shaun J. Kilty, et al.
Published: (2022-04-01)

M2 macrophage derived HMOX1 defines chronic rhinosinusitis with nasal polyps
by: Enhao Wang, et al.
Published: (2024-12-01)

Olfactory impairment in Italian patients with chronic rhinosinusitis with nasal polyps: a patient-centered survey
by: Francesca Anastasi, et al.
Published: (2025-01-01)

Peak nasal inspiratory flow assessment of polyp size and response from SYNAPSE
by: Amber U. Luong, MD, PhD, et al.
Published: (2024-11-01)

Long-term effects of dupilumab on chronic rhinosinusitis with nasal polyps: A step towards clinical remission
by: Mona Al-Ahmad, MD, FRCPC, et al.
Published: (2025-02-01)

Real-World Evaluation of Dupilumab in the Long-Term Management of Eosinophilic Chronic Rhinosinusitis with Nasal Polyps: A Focus on IL-4 and IL-13 Receptor Blockade
by: Nicola Lombardo, et al.
Published: (2024-12-01)

Relationship between serum ECP and TIgE levels and the risk of postoperative recurrence in patients with chronic rhinosinusitis with nasal polyps
by: Qing Zhang, et al.
Published: (2025-01-01)

Clinical evaluation of primary endoscopic frontal sinus surgery grade 6 (Draf III) in patients with moderate to severe eosinophilic chronic rhinosinusitis with polyps: a randomized study
by: Ibrahim Talal Elshamy, et al.
Published: (2024-12-01)

Chronic rhinosinusitis with nasal polyps (CRSwNP) symptom verbal response scales: content validity testing for use in adults with CRSwNP
by: Tom Keeley, et al.
Published: (2024-12-01)

Determining the Severity of Symptoms Among Patients with Eosinophilic Chronic Rhinosinusitis with Nasal Polyposis Versus Non - Eosinophilic Chronic Rhinosinusitis with Nasal Polyposis at the Veterans Memorial Medical Center
by: Geoffrey John Hizon, et al.
Published: (2024-11-01)

Evaluation of serum levels of Interleukin -1 and Tumor Necrosis Alpha (TNF-α) and their nucleotide polymorphisms in patients with chronic rhinosinusitis.
by: Abdelhakim Fouad Ghallab, et al.
Published: (2024-11-01)

Research progress in the establishment of mouse models of chronic rhinosinusitis
by: CHEN Yuan, SHEN Yang, WANG Ji, LU Tao, ZHENG Bowen, YANG Yucheng
Published: (2024-10-01)

Improving predictability of IgE-high type 2 chronic sinusitis with nasal polyps in the biologic era
by: Austin Heffernan, et al.
Published: (2022-05-01)

Unveiling and validating biomarkers related to the IL-10 family in chronic sinusitis with nasal polyps: insights from transcriptomics and single-cell RNA sequencing analysis
by: Xinghong Liu, et al.
Published: (2025-01-01)

Chronic Rhinosinusitis with Nasal Polyps and Biologics: A Call for Better Data Standardisation and Presentation in Clinical Studies
by: Kariyawasam HH, et al.
Published: (2025-01-01)

The “real life” efficacy of dupilumab is independent of initial polyp size and concomitant steroids in CRSwNP
by: Nicholas J. Campion, et al.
Published: (2023-09-01)

Dupilumab reduces patient-reported cough and improves quality of life in patients with severe eosinophilic asthma with or without chronic rhinosinusitis with nasal polyps: a real-life prospective study
by: Carlo Lombardi, et al.
Published: (2025-08-01)

Changes in the Microbiome During Chronic Rhinosinusitis
by: Mateusz de Mezer, et al.
Published: (2024-12-01)

Neutrophil extracellular traps as an important part of the pathogenesis of chronic rhinosinusitis without polyps
by: Valery М. Svistushkin, et al.
Published: (2024-10-01)

ADGRB3-High and POSTN-High Fibroblasts Are Markers of Endotypic Traits in Chronic Rhinosinusitis
by: Hideyuki Takahashi, et al.
Published: (2024-12-01)

Definition and characteristics of acute exacerbation in adult patients with chronic rhinosinusitis: a systematic review
by: Dawei Wu, et al.
Published: (2020-08-01)

Endoscopic sinus surgery outcomes in patients with chronic rhinosinusitis and immunoglobulin deficiencies
by: Shireen Samargandy, et al.
Published: (2023-06-01)

The argument against the use of dupilumab in patients with limited polyp burden in chronic rhinosinusitis with nasal polyposis (CRSwNP)
by: Scott A. Hardison, et al.
Published: (2023-09-01)

The potential role of Helicobacter pylori in chronic rhinosinusitis with or without nasal polyposis
by: Mohamed Ali Elsayed, et al.
Published: (2024-09-01)

Angiotensin-Converting Enzyme Insertion/Deletion Gene Polymorphism in Chronic Rhinosinusitis with Nasal Polyps
by: Mehmet Emre Sivrice, et al.
Published: (2024-09-01)

Remission: does it already exist in chronic rhinosinusitis with nasal polyposis?
by: Yvonne Chan, et al.
Published: (2023-07-01)

Label-Free Quantitative Proteomics Analysis of Nasal Lavage Fluid in Chronic Rhinosinusitis with Nasal Polyposis
by: Musallam Kashoob, et al.
Published: (2024-10-01)

Resection versus preservation of the middle turbinate in surgery for chronic rhinosinusitis with nasal polyposis: a randomized controlled trial
by: Marc-Antoine Hudon, et al.
Published: (2018-11-01)

Actinomycosis masquerading as a nasal polyp – a rare entity and diagnostic challenge
by: Sakthimohan, Revathy, et al.
Published: (2024-12-01)

Canadian Rhinology Working Group consensus statement: biologic therapies for chronic rhinosinusitis
by: Andrew Thamboo, et al.
Published: (2021-03-01)

A proposal for analyzing the inflammatory and remodeling processes of mucosa in chronic rhinosinusitis with nasal polyposis through MRI
by: Débora de Carvalho Garcez, et al.
Published: (2024-11-01)

Effect of platelet-rich plasma on recurrence of sinonasal polyps after endoscopic sinus surgery: a randomized clinical trial
by: Alaa Mohamed Abd El Samiea, et al.
Published: (2024-12-01)