RAD51 modulates in nasopharyngeal carcinoma cells by regulating Caspase-8-mediated pyroptosis

RAD51 modulates in nasopharyngeal carcinoma cells by regulating Caspase-8-mediated pyroptosis

Abstract Objective Radiotherapy is a first-line treatment for nasopharyngeal carcinoma (NPC), but resistance to radiation remains a major clinical challenge. This study aimed to investigate the role of RAD51, a key homologous recombination repair protein, in radiotherapy resistance of NPC and to elu...

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Bibliographic Details
Main Authors: Fuchuan Xie, Jian Song, Yunming Tian, Xinyu Zhang, Tanhuan Chen, Meng Xu
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
RAD51
Nasopharyngeal carcinoma
Radiotherapy
Pyroptosis
Caspase-8
Online Access:https://doi.org/10.1007/s12672-025-03100-2
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